COM – Intramural Grant Program

College of Medicine Intramural Grant Program

I. Purpose of the College of Medicine Intramural Grant Program
The Intramural Grant programs of the College of Medicine of the University of Arkansas for Medical Sciences are designed to advance the research mission of the institution and to provide seed money to full-time faculty members to advance and develop their individual research programs and careers in a variety of ways. In particular, intramural grants are designed to: 1) assist the researcher in obtaining extramural funding for new research programs by generating preliminary date; 2) protect and nurture existing extramural funding by providing bridging/interim support between funding periods for productive investigators; 3) assist in the acquisition of shared equipment to improve the position of College of Medicine researchers in competing for extramural funding.

II. General Conditions of Eligibility 
Awards are made only to full-time faculty members (including VA appointments) of the College of Medicine who are at the rank of instructor or above. Fellows, postdocs, and individuals in temporary positions are not eligible. Individuals at the level of instructor require a letter from the department Chairperson confirming that the individual is not in a temporary position and that the department intends to develop the individual as a faculty member. Recipients may hold only one College of Medicine intramural Grant at a time. Individual programs have additional eligibility requirements that are described below. Eligible faculty members may submit only one application per deadline on which they are Principal Investigator.


I. Pilot Study:
Description: The College of Medicine has established a Pilot Study grant program designed to assist and encourage new and existing faculty to develop research programs that can successfully compete for outside funding. The major objective of the Pilot Study program is to provide seed money to initiate a project and acquire the necessary preliminary data for submission of a major extramural grant application to a federal agency or national foundation. Collaborative efforts are encouraged such that investigators may apply for individual awards and the resources from these awards pooled to support new, joint research efforts. In this case, the unique contributions of each applicant to the collaboration must be made clear and the requirement for more than one grant to support the effort justified. Collaborative applications should be explicitly identified in the abstract. Collaborative applications with substantially identical research plans will not be reviewed. Maximum awards are limited to $25,000.

Eligibility and Additional Requirements: Subject to the restrictions given above, all full-time faculty members of the College of Medicine are eligible for Pilot Study grants. However, because the purpose of the program is to provide seed money to establish new projects capable of acquiring external support, it is expected that applications from new faculty will receive higher priority than those from established faculty. However, established faculty who intend to initiate a new program, individually or collaboratively, and who have been productive in the past in obtaining extramural funding, are encouraged to apply. Such priority will be at the discretion of the Research Council.

II. Bridging/Interim Funding
Description: The pursuit of extramural funding is highly competitive, and it is sometime unavoidable that a research program will experience a lapse in extramural support. Proposal resubmissions are often necessary which require response to reviewers’ comments and possibly acquisition of additional supporting data. A lapse in funding can severely affect the productivity of a research program and its long term viability, since experienced technicians may lose salary support during this period. The purpose of the Bridging/Interim Funding program is to minimize the adverse effects of this lapse by providing productive scientists with temporary funding. Support for PI salaries, graduate student salaries and travel may not be requested. Key research assistant/associates salaries are allowed, as well as supplies to conduct the research.

Eligibility and Additional Requirements: Awards are made only to full-time faculty members, as described above, of the College of Medicine with programs funded by a major federal agency or private foundation. Extramural funding must have expired less than 12 months from the submission date, but applications can be submitted before the expiration of prior funding, although not before an investigator has learned that a renewal will not be funded. The program is not applicable to investigators who received a 1-year grant from an extramural agency. Funding priorities for this program will reflect past success of the specific research program and the likelihood of continued funding. Thus, programs that have been repeatedly successful in renewing funding in the past, or that appear likely to be funded based on the current agency review, will receive high priority. The maximum award amount is limited to $45,000 and additional application requirements of this program are described below.

III. Hornick Endowment for Research into Stroke and Related Disorders 
Description: This program is designed to promote research into the causes, prevention, and treatment of stroke and related disorders. Hornick funds can be used to: 1) initiate research into new areas that currently are not funded extramurally: 2) support student research under the supervision of an established investigator; or 3) increase productivity in a currently funded program that has a high potential for scientific or medical impact.

Eligibility and Additional Requirements: Eligibility is as described above for College of Medicine Intramural Programs. The Research Plan (see below), in addition to the requirements outlined above, should clearly describe how the project relates to stroke or related disorders. Proposals will be judged by the general criteria given above for Pilot Studies and the probability of making a significant contribution to research, treatment, or prevention of stroke and related disorders. Typically only one award will be made per year from the Hornick Endowment. High quality proposals submitted to, but not funded by, the Hornick Endowment will automatically be considered for Pilot Study funding. Maximum awards are limited to $50,000 per year for up to 2 years.

IV. Equipment 
Description: The College of Medicine recognizes that state-of-the-art instrumentation is essential for conducting modern biomedical research capable of attracting extramural funding. Such instrumentation is increasingly expensive and difficult to acquire through normal extramural grant mechanisms. The purpose of this program is to provide a mechanism for researchers in the College of Medicine to obtain relatively small pieces of research equipment for shared use. Maximum award amount is limited to $30,000.

Eligibility and Additional Requirements: Applications will be accepted from groups of two or more full-time faculty members, as directed above, in the College of Medicine. One member should be designated Principal Investigator. Two possible situations are envisaged. In the first, a group of investigator’s requests funds to totally cover the cost of a shared piece of equipment. In the second, an investigator is submitting an extramural proposal requesting partial funding for purchase of a piece of research equipment. This investigator would recruit additional investigators for an intramural Equipment proposal to cover the additional funds necessary. Priority will be given to proposals that provide the greatest benefit to the largest number of researchers and that present a viable plan for shared equipment use and for maintenance.

V. Sturgis Grants for Diabetes Research
Description: This grant program, funded by the Sturgis Foundation, provides short-term funding for research on diabetes or the complications of diabetes. The maximum award amount is $25,000.

Eligibility and Additional Requirements: Applications are generally due in early January with projects beginning in February and ending by October. The project proposal must clearly explain how the project relates to diabetes or the complications of diabetes and must be feasible for completion in an 8-month period. Project findings will be reported to the College of Medicine in early October.


Submission and Evaluation: Contact the office of the Executive Associate Dean Research at 686-7459. Except for a request for Interim Funding, the deadlines for receipt of a completed application in the Office of the Executive Associate Dean for Research are the close of business on October 1 or April 1 of each year (or the next business day if these dates fall on a Saturday, Sunday or holiday). Proposals for Bridging/Interim Funding may be submitted at any time. Applicants for Interim Funding are advised that a proposal should be submitted at least three weeks in advance of the Research Council meeting (call 686-7459 for this information) at which the application will be considered.

Upon receipt, all applications will be referred to the Research Council of the College of Medicine for evaluation.

All intramural proposals submitted for a single deadline will be considered together. Proposals will be evaluated and ranked on the basis of scientific merit, potential for generation of extramural funding, and need, as well as the stated goals of the specific program. The results of the review process will be communicated to the applicant by letter from the College of Medicine Research Council Chairman, usually within 4 to 6 weeks of submission.

Pilot Study, Hornick, Bridging/Interim and Equipment Grant Submission: A signed original plus three (3) copies should be submitted to the office of the Executive Associate Dean for Research, Biomedical Research Center II, room 159-2, mail slot 718. Applications should be prepared carefully and completely. Incomplete applications or those which do not follow the required format will be returned without consideration. Photocopies of extramural grant applications will not be accepted as intramural applications.

Additional Requirements for Bridging/Interim Funding: The maximum award for the Interim Funding Program is $45,000. In addition to the above, every proposal must include a letter of support from the applicants department chair or division chief indicating their support for the applicant as well as a financial commitment of at least 1/3 of the requested amount from departmental/division funds. Proposals without a letter indicating departmental support will not be considered.

Applications will be rated: 1) approved for funding; 2) approved conditionally pending receipt of additional information; or 3) not approved for funding. Conditional approvals will be funded shortly after receipt of the additional information and its acceptance by the Research Council.

Award Periods: The award period for all intramural grants is one year. If any funds are remaining at the end of that period, a single six month extension may be requested by submitting a justification in writing to the Office of the Executive Associate Dean of Research. If an awardee receives significant funding from an extramural source for the research proposed in the intramural funding application, the unspent funds shall be returned to the College of Medicine.

Final Reports: In order to evaluate the effectiveness of its intramural programs, the Research Council requires that all intramural grant recipients submit a Final Report. This Final Report is due three months after the end of the award period, unless a no-cost extension has been granted. No applicant shall be eligible for further intramural awards without submission of a Final Report. After the conclusion of the award, the Executive Associate Dean for Research will request a list of pertinent publications and grant applications from the Awardee.


Preparing the Application: It is important that the applicant follow the required format and guidelines for proposal preparation. Well-written, concise proposals that clearly describe the research are more likely to receive favorable consideration. In preparing the application, follow the format and general guidelines below. Also, individual programs may have additional, specific requirements which must be addressed.

This page must be completed in its entirety. The applicant should check the program under which the application will be considered for funding.

ITEM 4: 
It is recommended that the applicant obtain all necessary approvals before submission, and attach the approval letter(s). Applications with pending approvals will be considered, but no application will be funded until all necessary approvals are obtained.

ITEM 5: 
Both the applicant and the Department Chairperson must sign the application. Signature acknowledges acceptance of the rules and requirements for proposal submission.

Please provide an abstract of 150-200 words that clearly and concisely describes the project.

On this page give a detailed budget for the project. Justify the amounts requested in each category. The Research Council disallows budget items that do not have a clear relevance to the research proposed. Travel is not normally allowed, unless it is intrinsic to the research effort. Faculty salaries are not allowed. For Equipment requests, describe any cost-sharing arrangements. Do not exceed one page.

A current biographical sketch of the Principal Investigator and each Co-Investigator in NIH format must be submitted with the application. Do not exceed four pages for each biographical sketch. Do not attach full CV’s.

PAGE 5 (add additional pages if necessary):
List all current and past institutional support. Attach an abstract and final report for all previous intramural grants for the College of Medicine.

PAGE 6 (add additional pages if necessary): 
List all active and pending extramural support. For each grant, list the title, source, total amount, percent effort, and grant period. List the status of pending applications, including any to the UAMS Medical Research Endowment Funds.

Note: If you are also submitting essentially the same proposal to the UAMS Medical Research Endowment Fund or other intramural funding source, please keep in mind that you cannot receive funding for the same work from two or more intramural funding sources. You can submit to both programs to fund fully a proposal with a budget in excess of the $25,000 maximum. In this case, please describe how you would apply both awards, if both should be funded, to cover the costs of project, and attach the budget submitted to the second intramural funding source.

If you are also submitting an extramural pilot proposal for funding of essentially the same work (for example, to a pilot study program of an outside foundation), you may be required to return all or part of a College of Medicine Intramural Grant Award, depending on circumstances, if the extramural pilot proposal is also funded.

Depending on the particular program, the Research Plan of the application should follow the appropriate format given below.

Research Plan (Pilot Study, Hornick):

A. Specific Aims: State concisely and realistically what the research described is intended to accomplish and what hypothesis is to be tested. Do not exceed 1 page.

B. Background and Significance: Briefly sketch the background to the present proposal, critically evaluate existing knowledge, and specifically identify gaps which the project is intended to fill. State concisely the importance of the research described in the application by relating the specific aims to long term objectives. Do not exceed 3 pages.

C. Methods: Discuss in detail the experimental design and the procedures to be used to accomplish the specific aims of the project. Describe the protocols to be used and the tentative sequences of the investigation. Include the means by which the data will be analyzed and interpreted. Describe any new methodology and its advantages over existing methodologies. Discuss the potential difficulties and limitations of the proposed procedures, and alternative approaches to achieve the aims. Describe any hazardous procedures or materials and the precautions to be taken. Do not exceed 5 pages.

D. Future Plans: Describe your plans for continuing or extending the work if the current project is successful. In particular, describe how the current work will support a plan for continued extramural funding. Give a possible title and specific aims for an extramural application and intended funding agencies. Do not exceed 1 page.

E. Literature Cited: In the text, number the references in order of appearance and provide the complete, numbered citations (including title of the article) in a list at this point. Do not exceed 2 pages.

F. Collaborators/Consultants: Attach a letter from each collaborator or consultant confirming his or her role on the project.

Research Plan (Interim Funding): 
A. A copy of the abstract and the Specific Aims Section of the grant submitted for extramural funding.

B. A copy of the review (e.g., NIH summary statement) from the funding agency.

C. A detailed plan for addressing the reviewers’ comments. This would normally include the intended written reply (e.g., the Introduction to a Revised Application to NIH), as well as a detailed research plan for additional experimental work necessary to address the reviewers comments.

Research Plan (Equipment): 
A. A detailed description of the equipment requested and the plans for meeting maintenance and operating costs should be described. Justification of the specific model should be given. A management and time-allocation plan, a list of primary users, the location, and any renovation costs would be provided. If similar pieces of equipment are available at UAMS, justify why anew acquisition is necessary. Do not exceed two pages.

B. For each project that will make use of the proposed equipment, provide a one-page description that includes the following: 1) the project principal investigator; 2) a brief scientific summary of the project; 3) how the project will utilize the proposed equipment; 4) how the overall project is or will be funded, i.e., give related external and internal grant information in the format given above.

C. A description of the benefits of the acquisition, particularly with regard to the generation of new extramural funding, or the protection of existing funding.


University of Arkansas for Medical Sciences College of Medicine
Intramural Grant Programs
Cover Page




Check appropriate program submission:

Program (check one):

____ Individual Pilot Study (Submission dates: October 1 and April 1; Submit original and 3 copies)

____Collaborative Pilot Study (Submission dates: October 1 and April 1; Submit original and 3 copies)

____Interim Funding (Bridging Grant) (Submission: anytime)(Submit original and 3 copies)

____Hornick Endowment (Submission dates: October 1 and April 1)(Submit original and 3 copies)

____Equipment (Submission dates: October 1 and April 1)(Submit original and 3 copies)

1. Title:



2. Principal Investigator information: UAMS/VA/ACH Address:




Department: Telephone: E-mail Address:


3. Budget Request: $


4. Committee Approvals: (Attach copies to proposal)


Animal Use: _____Yes ____Pending ____Not Applicable

Human Subjects: _____Yes ____Pending ____Not Applicable

Biosafety approval: _____Yes ____Pending ____Not Applicable (DNA & Biohazards)

Radioisotopes: _____Yes ____Pending ____Not Applicable

5. Signature:


Principal Investigator:_______________________________ Date:______________________


Department Chairperson:____________________________ Date:______________________






Principal Investigator:

Summary (100-150 word describing major results):

















Extramural Grants originating from this project (indicate whether awarded, submitted , in preparation):












Publications originating from this project (include those published, in press, or submitted, but not those in preparation):











Send completed form to: Dr. Charlotte Hobbs, 686-7459  or 364-5000, Mail Slot 550.