The ACNC has a large ~25,000 ft2 clinical facility, and a Clinical Research Core directed by Dr. Aline Andres and led by Clinical Coordinator, Elizabeth Hayes. The Core operates: an Outpatient Unit, an Inpatient Unit, Recruiting Program, Body Composition Laboratories, Clinical Nutrition Laboratory, Psychological Testing Group and Brain Function Facilities for measuring electrophysiological indices in infants and children. The Core is staffed by several full-time recruiters, three dietitians, a psychological examiner, data manager, registered nurse, and four technical research assistants. The Outpatient Unit has five clinic rooms, three interview rooms, two testing rooms with one-way mirror for observation to conduct psychological and behavioral testing, two indirect calorimetry units (MOXUS) suitable for infant and adult calorimetry, and three phlebotomy rooms. The Core has a dedicated laboratory to process human biological samples (including placenta, cord, blood, urine, feces, breastmilk, saliva, etc.) and is equipped with all key equipment including laminar flow hoods, incubators for cell culture, centrifuges, refrigerators/freezers, etc. The body composition laboratories have a BodPod, PeaPod, two DXA instruments (Hologic Horizon A and QDR4500), and a qNMR custom-built for infants and children (EchoMRI-AH). The Core maintains a quiet room for infant feeding that is equipped with a hospital grade breastmilk pump, four anthropometric measurement rooms, a space dedicated for the measurement of flow-mediated dilation using ultrasound technology, and office space for staff. Furthermore, the ACNC Inpatient Unit has a live-in center, with five overnight rooms with fully equipped bathrooms, lounge, large playroom, nurses’ station, dining room, and a kitchen. All IRB activities are administered through the UAMS system. A pQCT (for bone) and ultrasound are routinely used and made available for research, in collaboration with Arkansas Children’s Hospital clinics.