• Skip to main content
  • Skip to main content
Choose which site to search.
University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
College of Medicine: Department of Radiation Oncology
  • UAMS Health
  • Jobs
  • Giving
  • About Us
    • Contact Us
    • Maps and Directions
  • Faculty
    • Fen Xia, M.D., Ph.D.
    • Justin Wai Chung Leung, Ph.D., M.Sc.
    • Ruud P.M. Dings, Ph.D., M.Sc.
    • Richard Crownover, M.D., Ph.D.
    • Robert J. Griffin, Ph.D.
    • Leslie Harrell, D.O.
    • Sanjay Maraboyina, M.D.
    • Ganesh Narayanasamy, Ph.D.
    • Faraz Kalantari, Ph.D
    • Gary Lewis, M.D.
    • Pouya Sabouri, Ph.D.
    • Zhong Su, Ph.D.
    • Adam R. Wolfe M.D., Ph.D.
    • Charles Brown, Program Manager
  • Education
    • Medical Physics Residency
    • Medical Residency
      • Radiation Oncology Interest Group
      • Residents
        • Anam Kesaria, M.D.
        • Mausam Patel, M.D.
        • Arpan V. Prabhu, M.D.
        • Kaidi Wang, M.D.
      • How to Apply
    • Resident Wellness
    • Life in Little Rock
  • Research
    • Clinical Trials
    • Grants
    • Translational Research
      • Dings Lab
      • Griffin Lab
        • Publications
      • Xia Lab
        • Research
        • Publications
        • Members
        • Images
  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Radiation Oncology
  4. Faculty
  5. Justin Wai Chung Leung, Ph.D., M.Sc.

Justin Wai Chung Leung, Ph.D., M.Sc.

Justin Chung

Assistant Professor

Education and Training

  • B.Sc. (Biochemistry) –  Hong Kong University of Science and Technology
  • M.Sc. (Biotechnology) – Hong Kong University of Science and Technology
  • Ph.D. (Molecular Biology/Anatomy) – University of Hong Kong
  • Postdoctoral training  – Yale University, MD Anderson Cancer Center, University of Texas at Austin

Research Interests

  • DNA damage response (DDR) pathway
  • Chromatin biology
  • Epigenetics
  • Genome stability
  • Cancer Biology

Selected Publications

  1. Leung JW, Makharashvili N, Agarwal P, Pourpre R, Cammarata M, Cannon J, Sherker A, Durocher D, Brodbelt J, Paull TT & Miller KM. ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes and Development, 2017 Feb; 31:260-274.
  2. Huang Y, Leung JW, Lowery M, Matsushita N, Wang Y, Shen X, Huong D, Takata M, Chen J, Li L. Modularized functions of the Fanconi anemia core complex. Cell Reports. 2014 Jun 26;7(6):1849-57.
  3. Leung JW, Agarwal P, Canny MD, Gong, Robison AD, Finkelstein IJ, Durocher D & Miller KM. Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling. PLoS Genetics, 2014 Mar 6;10(3):e1004178.
  4. Wang Y, Han X, Wu F, Leung JW, Lowery MG, Do H, Chen J, Shi C, Tian C, Li L, Gong W. Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Research. 2013 Oct; 23(10):1215-28.
  5. Leung JW, Ghosal G, Wang W, Shen X, Li L, Chen J. Alpha thalassemia/mental retardaation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. Journal of Biological Chemistry. 2013 Mar 1;288(9):6342-50.
  6. Wang Y, Leung JW, Jiang Y, Lowery MG, Vasquez KM, Chen J, Wang W, Li L. FANCM and FAAP24 maintain genomic stability through cooperative as well as unique functions. Molecular Cell. 2013 Mar 7;49(5):997-1009.
  7. Ghosal G, Leung JW, Nair BC, Chen J. PCNA-binding protein C1orf124 is a regulator of translesion synthesis. Journal of Biological Chemistry, 2012 Oct 5;287(41):34225-33.
  8. Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proceeding of the National Academy of Sciences. 2012 Mar 20;109(12):4491-6 .
  9. Leung JW, Leitch A, Wood JL, Shaw-Smith C, Metcalfe K, Bicknell LS, Jackson AP, Chen J. SET nuclear oncogene associates with microcephalin/MCPH1 and regulates chromosome condensation. Journal of Biological Chemistry. 2011 Jun 17;286(24):21393-400.
  10. Huen MS, Huang J, Leung JW, Sy SM, Leung KM, Ching YP, Tsao SW, Chen J. Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1. Molecular Cell. 2010 Mar 26;37(6):854-64 .

Lab Webpage

UAMS College of Medicine LogoUAMS College of MedicineUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
  • Facebook
  • Twitter
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy

© 2022 University of Arkansas for Medical Sciences