University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
Department of Neurosurgery: Rodriguez Lab

Publications

  • Chiang VL, Pugazenthi S, Leidig WA, Rodriguez A, Prabhu S, Haskell-Mendoza AP, Fecci PE, Placantonakis DG, Abram SR, Lega B, Kim AH. Laser interstitial thermal therapy for new and recurrent meningioma: a prospective and retrospective case series. J Neurosurg. 2024 Mar 8:1-11. doi: 10.3171/2023.12.JNS231542. Epub ahead of print. PMID: 38457795.
  • Mathews AP, Shelton WJ, Horta ES, Reddy Damalcheruvu P, Nix JS, Gokden M, Rodriguez A. Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case. J Neurosurg Case Lessons. 2024 Feb 12;7(7):CASE23679. doi: 10.3171/CASE23679. PMID: 38346299; PMCID: PMC10865468.
  • Urbaniak A, Bathula C, Chauhan J, Rai P, Thammathong J, Clark C, Heflin B, De Loose A, Avaritt N, Rodriguez A, Tackett AJ, Sen S, Banerjee S. Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues. Chem Biodivers. 2023 Nov 23:e202301550. doi: 10.1002/cbdv.202301550. Epub ahead of print. PMID: 37994208.
  • McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Mol Cancer Ther. 2023 Oct 11. doi: 10.1158/1535-7163.MCT-23-0299. Epub ahead of print. PMID: 37816504.
  • Mahashabde R, Bhatti SA, Martin BC, Painter JT, Rodriguez A, Ying J, Li C. Real-World Survival of First-Line Immune Checkpoint Inhibitor Treatment Versus Chemotherapy in Older Patients With Non-Small-Cell Lung Cancer and Synchronous Brain Metastases. JCO Oncol Pract. 2023 Nov;19(11):1009-1019. doi: 10.1200/OP.23.00042. Epub 2023 Sep 20. PMID: 37729600.
  • Langston RG, Pinckard-Dover H, Guzman G, Wardell CP, Gokden M, Morris TW 3rd, Day JD, Rodriguez A. Intracranial hematolymphoid malignancies: A case series with molecular characterization. Clin Neurol Neurosurg. 2023 Oct;233:107928. doi: 10.1016/j.clineuro.2023.107928. Epub 2023 Aug 4. PMID: 37573681.
  • Pastorino NG, Tomatsu S, Lin A, Doerr J, Waterman Z, Sershen K, Ray P, Rodriguez A, Galileo DS. Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior. J Vis Exp. 2023 May 26;(195). doi: 10.3791/65199. PMID: 37306427.
  • Nassiri F, Patil V, Yefet LS, Singh O, Liu J, Dang RMA, Yamaguchi TN, Daras M, Cloughesy TF, Colman H, Kumthekar PU, Chen CC, Aiken R, Groves MD, Ong SS, Ramakrishna R, Vogelbaum MA, Khagi S, Kaley T, Melear JM, Peereboom DM, Rodriguez A, Yankelevich M, Nair SG, Puduvalli VK, Aldape K, Gao A, López-Janeiro Á, de Andrea CE, Alonso MM, Boutros P, Robbins J, Mason WP, Sonabend AM, Stupp R, Fueyo J, Gomez-Manzano C, Lang FF, Zadeh G. Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial. Nat Med. 2023 May 15. doi: 10.1038/s41591-023-02347-y. Epub ahead of print. PMID: 37188783.
  • Adler FR, Anderson ARA, Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks MC, Gartner ZJ, Germain RN, Gordon DM, Hunter G, Jolly MK, Karacosta LG, Mythreye K, Katira P, Kulkarni RP, Kutys ML, Lander AD, Laughney AM, Levine H, Lou E, Lowenstein PR, Masters KS, Pe’er D, Peyton SR, Platt MO, Purvis JE, Quon G, Richer JK, Riddle NC, Rodriguez A, Snyder JC, Lee Szeto G, Tomlin CJ, Yanai I, Zervantonakis IK, Dueck H. Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Syst. 2023 Apr 19;14(4):252-257. doi: 10.1016/j.cels.2023.03.002. PMID: 37080161.
  • Charles AJ, Seas A, Corley J, Duvall JB, Owolo E, Abu-Bonsrah N, Elsamadicy AA, Simpson V, Sanusi O, Holly LT, Rodriguez A, Nduom EK, Levi AD, Liau LM, Quiñones-Hinojosa A, Karikari I, Grant G, Fuller AT, Goodwin CR. Promoting diversity in neurosurgery through a virtual symposium. J Neurosurg. 2023 Mar 10:1-8. doi: 10.3171/2023.1.JNS221743. Epub ahead of print. PMID: 36905659.
  • Guzman G, Reed MR, Bielamowicz K, Koss B, Rodriguez A. CAR-T Therapies in Solid Tumors: Opportunities and Challenges. Curr Oncol Rep. 2023 Feb 28. doi: 10.1007/s11912-023-01380-x. Epub ahead of print. PMID: 36853475.
  • Guzman G, Pellot K, Reed MR, Rodriguez A. CAR T-cells to treat brain tumors. Brain Res Bull. 2023 Feb 23:S0361-9230(23)00048-5. doi: 10.1016/j.brainresbull.2023.02.014. Epub ahead of print. PMID: 36841424.
  • Al-Hamaly MA, Turner LT, Rivera-Martinez A, Rodriguez A, Blackburn JS. Zebrafish Cancer Avatars: A Translational Platform for Analyzing Tumor Heterogeneity and Predicting Patient Outcomes. International Journal of Molecular Sciences. 2023; 24(3):2288. https://doi.org/10.3390/ijms24032288
  • Sanders LM, Chandra R, Zebarjadi N, Beale HC, Lyle AG, Rodriguez A, Kephart ET, Pfeil J, Cheney A, Learned K, Currie R, Gitlin L, Vengerov D, Haussler D, Salama SR, Vaske OM. Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors. Commun Biol. 2022 Dec 13;5(1):1367. doi: 10.1038/s42003-022-04075-4. PMID: 36513728; PMCID: PMC9747808.
  • Urbaniak A, Reed MR, Heflin B, Gaydos J, Piña-Oviedo S, Jędrzejczyk M, Klejborowska G, Stępczyńska N, Chambers TC, Tackett AJ, Rodriguez A, Huczyński A, Eoff RL, MacNicol AM. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer. Biomed Pharmacother. 2022 Sep;153:113440. doi: 10.1016/j.biopha.2022.113440. Epub 2022 Jul 20. PMID: 36076555; PMCID: PMC9472755.
  • Rennert RC, Stephens ML, Palmer AW, Rodriguez A, Kazemi N, Morris TW 3rd, Pait TG, Day JD. Basilar decompression via a far lateral transcondylar approach: technical note. Acta Neurochir (Wien). 2022 Jul 22. doi: 10.1007/s00701-022-05312-9. Epub ahead of print. PMID: 35867183.
  • Tripathi SD, Parker PD, Prabhu AV, Thomas K, Rodriguez A. An Examination of Patients and Caregivers on Reddit Navigating Brain Cancer: Content Analysis of the Brain Tumor Subreddit. JMIR Cancer. 2022 Jun 22;8(2):e35324. doi: 10.2196/35324. PMID: 35731559.
  • Asfaw ZK, Rodriguez A, Hodges TR, Mazumdar M, Zhan S, Lim M, Germano IM. Diversity within the Neurosurgical Oncology Workforce in the United States: A Cross-Sectional Study with Proposed Strategies to Pave the Path Forward. Neuro Oncol. 2022 Jun 15:noac150. doi: 10.1093/neuonc/noac150. Epub ahead of print. PMID: 35705107.
  • Helton M, Thomas K, Sexton K, Rodriguez A, Porter A. Treatment Trends and Inpatient Mortality in Isolated Severe Traumatic Brain Injury Using the National Trauma Data Bank. World Neurosurg. 2022 May 18:S1878-8750(22)00678-7. doi: 10.1016/j.wneu.2022.05.048. Epub ahead of print. PMID: 35597537.
  • Brown CE, Rodriguez A, Palmer J, Ostberg JR, Naranjo A, Wagner J, Aguilar B, Starr R, Weng L, Synold TW, Tran V, Wang S, Reik A, D’Apuzzo M, Ressler JA, Zhou Y, Mendel M, Gregory PD, Holmes MC, Tang WW, Forman SJ, Jensen MC, Badie B. Off-the-shelf, Steroid Resistant, IL13Rα2-Specific CAR T Cells for Treatment of Glioblastoma. Neuro Oncol. 2022 Jan 31:noac024. doi: 10.1093/neuonc/noac024. Epub ahead of print. PMID: 35100373.
  • Reed MR, Lyle G, De Loose A, Maddukuri L, Learned K, Beale H, Kephart E, Cheney A, van den Bout A, Lee MP, Gokden M, Salama S, Wardell CP, Eoff RL, Vaske OM,  Rodriguez A. Functional precision medicine pipeline combines comparative transcriptomics and tumor organoid modeling to identify be-spoke therapeutic treatments for glioblastoma. Cells. 2021. In Press.
  • Wardell CP, Darrigues E, De Loose A, Lee MP, Gokden G, Makhoul I, Tackett AJ, Rodriguez A. Genomic and Transcriptomic Profiling of Brain Metastases. Cancers. 2021. 13(22):5598. doi: 10.3390/cancers13225598.
  • Darrigues E, Zhao EH, De Loose A, Lee MP, Borrelli MJ, Eoff RL, Galileo DS, Penthala NR, Crooks PA, Rodriguez A. Biobanked Glioblastoma Patient-Derived Organoids as a precision medicine model to study inhibition of invasion.  International Journal of Molecular Sciences. 2021. 22(19):10720. doi: 10.3390/ijms221910720.
  • Langston RG, Wardell CP, Palmer A, Scott H, Gokden M, Pait TG, Rodriguez A. Primary glioblastoma of the cauda equina with molecular and histopathological characterization: case report. NeuroOncology Advances. 2021. 3(1):vdab154. doi: 10.1093/noajnl/vdab154
  • Sanders S, Herpai DM, Rodriguez A, Huang Y, Chou J, Seals D, Mott R, Miller L, Debinski W. The Presence and Potential Role of ALDH1A2 in Glioblastoma Microenvironment. Cells. 2021. 10(9):2485.
  • Hundley KN, Rodriguez A, Day JD, Pait TG. Dr. Louise Eisenhardt’s Personal Notes: How She and Dr. Cushing collected data and followed patients. Journal of Neurosurgery. 2021. Sep 24:1-6. doi: 10.3171/2021.4.JNS201086. Online ahead of print.
  • Prabhu AV, Lee M, Galhardo E, Newkirk M, Rodriguez A, Xia F. Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine. Surg Neurol Int. 2021. 12:280. doi: 10.25259/SNI_589_2020
  • Hundley KN, Rodriguez A, Day JD, Pait TG. Dr. Louise Eisenhardt’s Personal Notes: How She and Dr. Cushing collected data and followed patients. Journal of Neurosurgery. 2021. Sep 24:1-6. doi: 10.3171/2021.4.JNS201086. Online ahead of print.
  • Sanders S, Herpai DM, Rodriguez A, Huang Y, Chou J, Seals D, Mott R, Miller L, Debinski W. The Presence and Potential Role of ALDH1A2 in Glioblastoma Microenvironment. Cells. 2021. 10(9):2485.
  • Langston RG, Wardell CP, Palmer A, Scott H, Gokden M, Pait TG, Rodriguez A. Primary glioblastoma of the cauda equina with molecular and histopathological characterization: case report. NeuroOncology Advances. 2021. 3(1):vdab154. doi: 10.1093/noajnl/vdab154
  • Darrigues E, Zhao EH, De Loose A, Lee MP, Borrelli MJ, Eoff RL, Galileo DS, Penthala NR, Crooks PA, Rodriguez A. Biobanked Glioblastoma Patient-Derived Organoids as a precision medicine model to study inhibition of invasion.  International Journal of Molecular Sciences. 2021. 22(19):10720. doi: 10.3390/ijms221910720.
  • Wardell CP, Darrigues E, De Loose A, Lee MP, Gokden G, Makhoul I, Tackett AJ, Rodriguez A. Genomic and Transcriptomic Profiling of Brain Metastases. Cancers. 2021. 13(22):5598. doi: 10.3390/cancers13225598.
  • Reed MR, Lyle G, De Loose A, Maddukuri L, Learned K, Beale H, Kephart E, Cheney A, van den Bout A, Lee MP, Gokden M, Salama S, Wardell CP, Eoff RL, Vaske OM,  Rodriguez A. Functional precision medicine pipeline combines comparative transcriptomics and tumor organoid modeling to identify be-spoke therapeutic treatments for glioblastoma. Cells. 2021. In Press.
  • Darrigues E, Elberson BW, De Loose A, Lee MP, Green E, Benton AM, Sink LG, Scott H, Gokden M, Day JD, Rodriguez A. Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon. Frontiers in Oncology. 2021. April 26 Epub ahead of print
  • Rennert RC, Khani M, Thomas K, Morris TW, Rodriguez A, Day JD. Transsulcal parafascicular brain path assisted approach to subcortical lesions: 2-dimensional operative video.  Surg Neurol Int. 2021. Mar 17. doi: 10.25259/SNI_776_2020. eCollection 2021.
  • Nduom EK, Gephart MH, Chheda MG, Suva ML, Amankulor N, Battiste JD, Campian JL, Dacey RG, Das S, Fecci PE, Hadjipanayis CG, Hoang KB, Jalali A, Orringer D, Patel AJ, Placantonakis D, Rodriguez A, Yang I, Yu JS, Zipfel GJ, Dunn GP, Leuthardt EC, Kim AH. Re-evaluating biopsy for recurrent glioblastoma. A position statement by the Christopher Davidson Forum Investigators.  Neurosurgery. 2021. April 16 online ahead of print
  • Niebles-Bedolla E, Christophers B, Williams JR, Power-Hays A, Jimenez N, Rodriguez A. Racial and Ethnic Disparities Among Children with Primary Central Nervous System Tumors in the US. Journal of Neuro-oncology. 2021. 152(3):451-466.
  • Rennert RC, Brandel MG, Stephens ML, Rodriguez A, Morris TW, Day JD.  Surgical Relevance of the suprameatal tubercle during superior petrosal vein sparing trigeminal nerve microsvascular decompression.  Operative Neurosurgery. 2021. Epub ahead of print
  • Taylor EM, Byrum SD, Edmondson JL, Wardell CP, Griffin BG, Shalin SC, Gokden M, Makhoul I, Tackett AJ, Rodriguez A. Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta Neuropathol Commun. 2020 Sep 5;8(1):157. doi: 10.1186/s40478-020-01029-x. PMID: 32891176; PMCID: PMC7487560.
  • Langston RG, Zhao EH, Wong KH, Rodriguez A. Recent trends in NIH funding for top surgeon-scientists. Am J Surg. 2020 Dec 4:S0002-9610(20)30782-0. doi: 10.1016/j.amjsurg.2020.12.004. Epub ahead of print. PMID: 33309253.
  • Gunasekaran A, Somasundarum A, Abu-Rmaileh M, Liu A, Pait TG, Tatter SB, Quest DO, Rodriguez A. The Original Cushing Society: A Historical Review of the Senior Society’s First 6 Meetings. World Neurosurg. 2020 Dec 8:S1878-8750(20)32512-2. doi: 10.1016/j.wneu.2020.11.127. Epub ahead of print. PMID: 33307257.
  • Patterson JD, Henson JC, Breese RO, Bielamowicz KJ, Rodriguez A.  CAR T cell therapy for pediatric brain tumors. Front Oncol. 2020 Aug 12;10:1582. doi: 10.3389/fonc.2020.01582. PMID: 32903405; PMCID: PMC7435009.
  • Patterson JD, Helton M, Khani M, Sardar S, Thomas K, Galhardo EP, Penagaricano JA, Day JD, Rodriguez A. Neurosurgical Management of Perineural metastases: a case series and review of the literature. Surgical Neurology International. 2020 Jul 25;11:206. doi: 10.25259/SNI_146_2020. PMID: 32874709.
  • Helton, M, Abu-Rmaileh M, Thomas K, Gokden M, Kanaan A, Rodriguez A.  Pituitary metastatic composite tumors: a case report with next generation sequencing and review of the literature. Case Reports in Oncological Medicine.  2020 Jul 21;2020:5073236. doi: 10.1155/2020/5073236. PMID: 32774962.
  • Wongsurawat T, Jenjaroenpun P, De Loose A, Alkam D, Ussery DW, Nookaew I, Leung YK, Ho SM, Day JD, Rodriguez A. A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma. Acta Neuropathologica Communications. 2020. 8(1):87.
  • Porter A, Brown CC, Tilford JM, Thomas K, Maxson RT, Sexton K, Karim S, Zohoori N, Rodriguez A.  Association of insurance status with treatment and outcomes in pediatric patients with severe traumatic brain injury.  Critical Care Medicine. 2020. 48(7): e584-e591.
  • Khani M, Hundley K, Morris TW, Henson JC, Thomas K, Wong KH, Rodriguez A, Day JD.  Surgical treatment of symptomatic small medial petrous meningiomas causing trigeminal neuralgia.  World Neurosurgery. 2020: S1878-8750 (2):20834-2.
  • Patterson JD, Wongsurawat T, Rodriguez A. A Glioblastoma Genomics Primer for Clinicians. Medical Research Archives. 2020. 8(2): 10.18103/mra.v8i2.2034.
  • Morris TW, Hundley KN, Thomas KO, Lockhart EC, Rodriguez A, Day JD. Decompression of Cavernous Sinus for Trigeminal Neuropathic Pain from Perineural Spread of Tumor: 2-Dimensional Operative Video. Operative Neurosurgery. 2020. Opaa033. PMID: 32147730
  • Darrigues E, Nima ZA, Griffin RJ, Anderson JM, Biris AS, Rodriguez A. 3D cultures for modeling nanomaterial-based photothermal therapy.  Nanoscale Horizons. 2020. 5(3): 400-430.
  • Gomez-Acedevo H, Patterson JD, Sardar S, Das B, Gokden M, Ussery D, Rodriguez A. SMARC-B1 deficient sinonasal carcinoma metastasis to the brain with next generation sequencing data: a case report of perineural invasion progressing to leptomeningeal invasion.. BMC Cancer. 2019; 19(1):827.
  • Thomas K, Wong KH, Steelman SC, Rodriguez A. Surgical Risk Assessment and Prevention in Elderly Spinal Deformity Patients. Geriatric Orthopaedic Surgery and Rehabilitation. 2019. May 22; 10.
  • Mirzaei H, Rodriguez A, Brown CE. Badie B. Corrigendum: Chimeric Antigen Receptors T Cell Therapy in solid tumors: Challenges and Clinical applications  Frontiers in Immunology. 2019. 10:780.
  • Wilson TA, Langston RG, Wong KH, Rodriguez A. Characteristics and career outcomes of NREF research fellowship recipients. Journal of Neurosurgery. 2019. Feb 8: 1-7.
  • Howe A, Kiffer F, Alexander TC, Sridharan V, Wang J, Ntagwabira F, Rodriguez A, Boerma M, Allen AR. Long Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation. Int J Mol Sci. 2019. 20(1): E188.
  • Alexander TC, Kiffer F, Groves T, Anderson J, Wang J, Hayar A, Chen MT, Rodriguez A, Allen AR.  Effects of thioTEPA chemotherapy on cognition and motor coordination. Synapse. 2018. Epub ahead of print.
  • Renfrow JJ, Rodriguez A, Wilson TA et al. Tracking Career Paths of Women in Neurosurgery. Neurosurgery. 2018. 82 (4):576-582.
  • Rodriguez A, Brown CE, Badie B. Chimeric Antigen Receptor T cell Therapy for Glioblastoma. Translational Research. 2017. 187: 93-102.
  • Mirzaei H, Rodriguez A, Brown CE. Badie B. Chimeric Antigen Receptors T Cell Therapy in solid tumors: Challenges and Clinical applications  Frontiers in Immunology. 2017. 8:1850