• Skip to main content
  • Skip to main content
Choose which site to search.
University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
Department of Pediatrics: Neonatology
  • UAMS Health
  • Jobs
  • Giving
  • About Us
  • Education and Training
    • NICU Guidebook
  • Faculty
  • Fellowship
  • Neonatology Research
  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Pediatrics
  4. Specialties
  5. Sections
  6. Neonatology
  7. Neonatology Research

Neonatology Research

Current Research Studies

DOVE — Drager Oscillatory Ventilation Evaluation

Sponsor: Drager Inc.

Location: UAMS and ACH

Inclusion Criteria:

  • Gestational Age at birth: 23 – 30 weeks
  • Birth weight: 400 – 1200 grams
  • Chronologic Age: less than 96 hours
  • 5-minute Apgar > 3
  • Clinician would like HFOV

Exclusion Criteria:

  • Already ventilated ≥ 96 hours
  • Major respiratory or cardiac anomalies
  • Pre-existing air leak
  • Known grade III/IV IVH

Contact any of the following:

  • Dr. Courtney 631-682-0812
  • Denise Pearson: 501-364-1065

Sildenafil for PPHN

Sponsor: Pfizer Labs

Location: ACH

Inclusion Criteria:

  • Gestational Age at birth: 34 weeks or greater
  • Chronologic Age: less than 96 hours
  • Diagnosis of PPHN on iNO

Exclusion Criteria:

  • Life-threatening anomalies
  • Diaphragmatic hernia
  • 5-minute Apgar Score < 5

Contact either:

  • Allen Harrison: 501-364-7192 or 404-734-3777 (text preferred) or pager 405-0829
  • Dr. Courtney: 631-682-0812 (text okay)

HIP — Hernia in Premies

Sponsor: Vanderbilt University

Location: ACH and UAMS (for recruitment)

Inclusion Criteria:

  • Gestational Age at birth: less than 37 weeks
  • The presence of an inguinal hernia

Exclusion Criteria:

  • Major anomalies
  • Simultaneous other surgery planned for hernia repair

Contact any of the following:

  • Dr. Dassinger:501-364-2943
  • Kathy Hummel:501-364-2715

Furosemide — Safety in Premature Infants at Risk of Bronchopulmonary Dysplasia

Sponsor: NIH/NICHD and the Pediatric Trials Network

Location: ACH

Inclusion Criteria:

  • Gestational Age at birth: less than 29 weeks
  • Chronologic age: 7–28 days
  • On nCPAP, NIPPV, NC, or mechanical ventilation

Exclusion Criteria:

  • Previous diuretics
  • Significant PDA
  • Certain abnormal lab at admission

Contact any of the following:

  • Andrea Ross: 501-364-3122
  • Dr. Courtney: 631-682-0812

Remodulin — Intravenous Remodulin (Treprostinil) as Add-On Therapy for the Treatment of PPHN

Sponsor: United Therapeutics

Location: ACH

Inclusion Criteria:

  • Gestational age ≥ 34 weeks and weight ≥ 2 kg
  • Chronologic Age: ≤ 14 days
  • Diagnosis of PPHN and currently requiring ventilator support
  • Two consecutive OIs of 15 or greater separated by at least 30 minutes, after receiving iNo for at least 3 hours

Exclusion Criteria:

  • Significant congenital heart disease (CHD)
  • Uncontrolled coagulopathy and/or untreated thrombocytopenia
  • History of severe (Grade 3 or 4) intracranial hemorrhage

Contact any of the following:

  • Allen Harrison: 501-364-7192 or 404-734-3777 (text preferred) or pager 405-0829
  • Dr. Courtney: 631-682-0812

PaTTerN Registry — Use of iNO in infants

Sponsor: Malenkrodt

Location: ACH and UAMS

  • A multicenter observational registry of premature (27 to 34 weeks) and term or near-term infants (34 to 40 weeks) with pulmonary hypertension who are receiving inhaled nitric oxide by either invasive or non-invasive ventilator support.

Contact any of the following:

  • Dr. Courtney 631-682-0812
  • Denise Pearson: 501-364-1065

Tele-intubation Study

Sponsor: NIH/NIGMS (National Institute for General Medical Sciences)

Location: UAMS

Inclusion Criteria:

  • Pediatric and Med-Peds Residents
  • Willing to participate during NICU rotation

Contact:

  • Dr. Whit Hall, 501-296-1397
  • Jimmy Birdsong, RN, 501-526-7838

Early Diagnosis of Acute Kidney Injury Using Urinary Biomarkers and Renal Oximetry in Neonates with HIE

Sponsor: ACRI

Location: ACH

Inclusion Criteria:

  • Gestational Age at birth ≥ 36 weeks
  • Receiving active or passive cooling prior to 6 hours of age
  • Perinatal depression/moderate to severe encephalopathy

Exclusion Criteria:

  • < 1800 g
  • Known severe renal anomaly
  • Severe congenital anomalies

Contact any of the following:

  • Dr. Jenny Rumpel: 630-363-8963
  • Dr. Courtney: 631-682-0812

Closed to New Enrollment

PENUT Trial — Preterm Epo Neuroprotection

Sponsor: NIH/NINDS

Location: UAMS and ACH

All PENUT patients will be followed through two years corrected age
Follow-up is in progress

SCAMP — Antibiotic Safety in Infants with Complicated Intra-Abdominal Infections (SCAMP)

Sponsor: NIH/NICHD and the Pediatric Trials Network

Location: ACH

Data analysis and follow-up are in progress

IBT — A Trial of Lactobacillus reuteri (A Probiotic) in Preterm Infants

Sponsor: Infant Bacterial Therapeutics

Location: UAMS and ACH

Data analysis is in progress; Phase III randomized trial starting soon

AEROSURF — Aerosolized Surfactant for Treatment of RDS

Sponsor: Discovery Labs

Location: UAMS

Data analysis is in progress

UAMS College of Medicine LogoUAMS College of MedicineUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
  • Facebook
  • Twitter
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy Statement

© 2023 University of Arkansas for Medical Sciences