The Burdine Laboratory is located at the Arkansas Children’s Research Institute. The lab is focused on understanding immunological mechanisms that drive solid organ transplant rejection to identify improved therapeutics for rejection prevention. The laboratory engages in in vitro cell-based assays as well as in vivo animal studies using both mice and pigs as model systems. In addition, the lab is embarking on a unique “operating room to bench” project to elucidate the proteomic signatures of all GI cancers. This is performed in collaboration with surgeons at Winthrop P. Rockefeller Cancer Institute and the UAMS pathology and proteomics core.