Assistant Professor
Department of Biochemistry and Molecular Biology
UAMS College of Medicine
Co-Director, Winthrop P. Rockefeller Cancer Institute Proteomics Shared Resource and UAMS Proteomics Core Facility
Research Interest Statement
My research interests are focused on proteomics and mass spectrometry. As co-director of the Proteomics Shared Resource and UAMS Proteomics Core Facility, I am involved in a wide variety of basic and translational research projects and collaborations at any given time. The core facility maintains and operates five state-of-the-art mass spectrometers, two of which I secured for the facility with NIH shared instrument grants. The core lab offers cutting-edge, affordable proteomics analysis to all UAMS investigators and Cancer Institute members. Our facility is nationally recognized with users in 35 states and Puerto Rico, and our research is routinely published in high-impact, peer-reviewed journals. We work closely with other researchers to help them design proteomics experiments, apply for grants and publish papers. We offer complete sample processing services so that our collaborators can submit samples they can easily prepare in their own labs. We also work closely with the UAMS Bioinformatics Core to prepare data for our collaborators in publication-ready formats.
Dr. Mackintosh’s Cancer–related Grants
NIH/NIGMS: 1S10OD026736
Samuel Mackintosh: Project PI
Title “Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer”
08/01/2019 to 07/31/2020
$763,961*
*project direct cost
As part of Dr. Mackintosh’s role as co-director of the Winthrop P. Rockefeller Cancer Institute Proteomics Shared Resource and UAMS Proteomics Core Facility, he also serves as Co-I on the ACRI/UAMS COBRE grant (Center for Translational Pediatric Research, PI: Alan Tackett PhD., NIH award P20GM121293) and the UAMS INBRE grant (Partnerships for Biomedical Research in Arkansas, PI: Larry Cornett PhD., NIH award P20GM103429).
Dr. Mackintosh’s UAMS Collaborators
- College of Medicine
- Department of Internal Medicine
- John Arthur, M.D., Ph.D.
- Jawahar Mehta, M.D., Ph.D.
- Department of Geriatrics
- Srinivas Ayyadevara, Ph.D.
- Richard Dennis, Ph.D.
- Robert Reis, Ph.D.
- Department of Biochemistry and Molecular Biology
- Giulia Baldini, Ph.D.
- Marie Burdine, Ph.D.
- Alicia Byrd, Ph.D.
- Stephanie Byrum, Ph.D.
- Tim Chambers, Ph.D.
- Rick Edmondson, Ph.D.
- Robert Eoff, Ph.D.
- Samantha Kendrick, Ph.D.
- Grover Miller, Ph.D.
- Kevin Raney, Ph.D.
- Aaron Storey, Ph.D.
- Alan Tackett, Ph.D.
- Wayne Wahls, Ph.D.
- Boris Zybaylov, Ph.D.
- Department of Neurobiology and Developmental Sciences
- Edgar Garcia-Rill, Ph.D.
- Angus MacNicol, Ph.D.
- Department of Biochemistry and Molecular Biology
- Renny Lan, Ph.D.
- Department of Pathology
- Mayumi Nakagawa, M.D., Ph.D.
- Steven Post, Ph.D.
- Department of Physiology and Biophysics
- Roy Morello, Ph.D.
- Department of Microbiology and Immunology
- Mark Smeltzer, Ph.D.
- Department of Internal Medicine
- College of Pharmacy
- Department of Pharmaceutical Sciences
- Martin Hauer-Jensen, M.D., Ph.D.
- Department of Pharmaceutical Sciences
- College of Public Health
- Department of Environmental and Occupational Health
- Mitch McGill, Ph.D.
- Gunnar Boysen, Ph.D.
- Department of Environmental and Occupational Health
Dr. Mackintosh’s External Collaborators
- Randy Haun, Ph.D., Arkana Laboratories
- Jeffrey Lewis, Ph.D., UA-Fayetteville
- Arthur Salomon, Ph.D., Brown University
- Sean Taverna, Ph.D., Johns Hopkins University
- Greg Wang, Ph.D., University of North Carolina
- Michael Wang, M.D., MD Anderson Cancer Center
- Michael Washburn, Ph.D., Stowers Institute for Medical Research
- Andrew Xiao, Ph.D., Yale University
- Qin Yan, Ph.D., Yale University
- Daohong Zhou, M.D., University of Florida
Opportunities for Collaboration
The resources of the Proteomics Core are available to anyone at UAMS, and there are pilot funding opportunities available for Cancer Institute members.