Overview
One of the few dedicated pediatric exercise physiology labs in the nation. This lab houses equipment necessary for exercise physiology studies, phlebotomy, and vital signs. The Laboratory for Active Kids and Families is a state-of-the-art ~1,400 sq ft pediatric exercise physiology lab, fully equipped for metabolic and fitness phenotyping. It operates within the broader Physical Activity and Metabolism Core, which includes a complementary ~1,800 sq ft Fitness Facility designed to support diverse research and real-world interventions.
Group Members
- Elisabet Borsheim, Ph.D., Core Director
- Eva Diaz, M.D., MMSc, Instructor
- Timothy J. Edwards, M.S., ACSM-RCEP, Exercise Physiologist
- Mandeepa Kumawat, M.S., Exercise Physiologist
Cardiorespiratory Fitness
Cardiorespiratory fitness is a key indicator of metabolic and cardiovascular health. We measure maximal or peak oxygen uptake using indirect calorimetry (Ultima PFX Cardio 2, MedGraphics) while participants exercise on a treadmill or cycle ergometer. The system is also used for submaximal exercise tests and resting metabolic measurements, providing insight into aerobic capacity and overall energy expenditure.
Muscle Strength
Muscle strength is essential for physical function and overall health. We assess muscular force using a dynamometer (Humac Norm, CSMi), which measures concentric, eccentric, isometric, and isokinetic contractions of different muscle groups. Handgrip strength is measured with a hydraulic hand dynamometer (Jamar) to evaluate upper-body strength.
Balance
Balance is evaluated using a computerized system (Humac Balance, CSMi), which allows tests such as limits of stability, random motion, and weight-shifting tasks. These assessments help identify deficits in coordination and postural control.
Flexibility
Flexibility is assessed with the sit-and-reach test (Lafayette Instruments), commonly used for children. Additional manual flexibility tests can be performed depending on the specific research study requirements.
Lung Function
We assess lung function using spirometry (Ultima PFX, MedGraphics) to measure parameters like forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and peak expiratory flow. The lab can also determine lung diffusion capacity, evaluating how efficiently oxygen moves from the lungs into the bloodstream.
Flow-mediated Dilation (FMD)
Endothelial function is measured using ultrasound (GE Vivid 7, 5.0–13.0 MHz linear transducer, GE Healthcare) to assess brachial artery flow-mediated dilation (FMD). This non-invasive technique visualizes artery diameter and evaluates vascular health.
Resting Energy Expenditure
Resting metabolic rate is measured using indirect calorimetry, which calculates energy expenditure from oxygen consumption (VO2) and carbon dioxide production (VCO2). Pediatric participants wear a face mask while resting in a quiet, temperature-controlled room, providing accurate baseline metabolic measurements.
Fibroscan, Sitting Height and Actigraph measurements are also available