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  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Biochemistry and Molecular Biology
  4. Department News
  5. Page 26

Department News

On the cover

Congratulations to graduate student Tresor Mukiza and his co-authors, Reine Protacio, Mari Davidson, Walter Steiner and Wayne Wahls.  Cover art for their new article on chromosome dynamics is featured on the home page of Genetics for November, 2019.  The editors also selected this paper to be featured in a highlight in Genetics.

Filed Under: Department News

October publications

Members of the Chambers labThe response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex vivo study.

Urbaniak A, Jousheghany F, Yuan Y, Piña-Oviedo S, Huczyński A, Delgado M, Kieber-Emmons T, Monzavi-Karbassi B, Chambers TC.

Oncol Lett.

Members of Miller labComprehensive Kinetic and Modeling Analyses Revealed CYP2C9 and 3A4 Determine Terbinafine Metabolic Clearance and Bioactivation.

Barnette DA, Davis MA, Flynn N, Pidugu AS, Joshua Swamidass S, Miller GP.

Biochem Pharmacol.

 

 

 

Wahls labTargeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast.

Storey AJ, Wang HP, Protacio RU, Davidson MK, Wahls WP.

G3 (Bethesda).

 

Members of the Chambers labSynthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents.

Klejborowska G, Urbaniak A, Preto J, Maj E, Moshari M, Wietrzyk J, Tuszynski JA, Chambers TC, Huczyński A.

Bioorg Med Chem.

 

Filed Under: Department News

Allie Davis and Dusty Barnette win at GSA Research Symposium

Dusty Barnette won third in the poster presentations, and Allie Davis won first in the oral presentations at the GSA Research Symposium.  Dusty and Allie are both students in Dr. Grover Paul Miller‘s lab.  Congratulations!

Filed Under: Department News

Miller lab attends Society of Toxicology meeting

Graduate students Dusty Barnette and Allie Davis, along with Laura Osborn (SURF student), Sasin (Copter) Payakachat (SURF student), and Anna Pinson (INBRE student) attended the Society of Toxicology – South Central Chapter Conference at Louisiana State University Health Sciences Center October 17-18. They are all students in Paul Miller‘s lab. Allie, Laura, and Sasin received travel awards.

Dusty presented a poster entitled “C5 Methyl Substituent Alters Which Enzymes Bioactivate Meloxicam Compared to Sudoxicam”. Laura presented a poster entitled “Multiple Metabolic Pathways Decrease Meloxicam Toxicity Relative to Analog, Sudoxicam”. Sasin presented a poster entitled “Identifying How Halogens Impact Bioactivation of Aryl Acetic Acid Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)”. Anna presented a poster entitled “Highly Efficient and Extensive Metabolism of Synthetic Cannabinoid 5F-APINACA Experiences Substrate Inhibition at High Concentrations”. Allie presented a talk entitled “Bioactivation of Halogenated Aromatic Drugs as a Precursor to Drug-Induced Hepatotoxicity”.

Filed Under: Department News

Happy Birthday Dr. Raney!

We had an impromptu celebration for Dr. Raney’s birthday.  Thanks Sharon and Kahla for the birthday treats.

Filed Under: Department News

September publications

Members of the Chambers lab

The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex vivo study

Alicja Urbaniak, Fariba Jousheghany, Youzhong Yuan, Sergio Piña‑Oviedo, Adam Huczyński, Magdalena Delgado, Thomas Kieber‑Emmons, Behjatolah Monzavi‑Karbassi, Timothy C. Chambers

Oncology Letters


Wahls lab

Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway.

Mukiza TO, Protacio RU, Davidson MK, Steiner WW, Wahls WP.

Genetics.


Tackett lab

Histone Modifications as Biomarkers for Immunotherapy.

Taylor EM, Koss B, Davis LE, Tackett AJ.

Methods Mol Biol

Filed Under: Department News

Village Walk for Cancer Research

The biochemistry department participated in the 18th Annual Village Walk for Cancer Research in Hot Springs Village.  The walk is a fundraiser for cancer research at WPRCI.  Funds from last years walk are currently funding a project addressing drug resistance in lymphoma in Samantha Kendrick‘s lab.  Also walking were Stephanie Byrum, Alicia Byrd, and Tung-chin Chiang.

Filed Under: Department News

Department welcomes new students with picnic

The Biochemistry and Molecular Biology welcomed new GPIBS students to UAMS with a picnic at Allsopp Park.  Thanks to students Katie Bronson and Allie Davis for helping with the organization and set up.

Filed Under: Department News

Allie Davis and Binyam Belachew receive white coats

Allie Davis, a graduate student in Dr. Paul Miller’s lab, and Binyam Belachew, a graduate student in Dr. Kevin Raney’s lab received their white coats at the UAMS Graduate School’s annual Research Induction Ceremony celebrating Ph.D. candidates who have successfully passed their qualifying exam in the past year.  Congratulations Allie and Binyam!

Filed Under: Department News

Allie Davis Elected to Two Professional Groups

Allie Davis, a graduate student in Dr. Grover Paul Miller’s lab has recently been elected to two different groups.

Allie was elected to serve on the International Society for the Study of Xenobiotics (ISSX) New Investigator Group. This group comprises promising new investigators (predoctoral, postdoctoral, and new to their careers) that recruit and retain new ISSX members and promote interaction and collaborations between new members and more experienced members to ensure a lively and diverse group for many years to come. Currently, the new investigator group is writing up a conference proceedings paper that covers the ISSX international meeting from this past July.

Allie was also selected to serve on the Drug Metabolism Reviews (DMR) editorial board. Being a predoctoral student, access to many editor friends and colleagues she’s met at conferences and events will help her to learn the editorial process. Allie was selected for this group because she is a promising new investigator who has shown that she is willing and able to communicate and collaborate with scientists across many branches with varying degrees of experience.

Congratulations Allie!

Filed Under: Department News

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