Supported by funds from the UAMS College of Medicine, the CMIC Pilot Project Program continues to identify researchers with ideas that align with the mission of the center and that could serve as a foundation for a full-fledged COBRE research project. To help these ideas mature and obtain key preliminary results, the CMIC funds up to two $75,000 Pilot Project awards annually.
In 2025, two projects were selected for Pilot Project funding.
Dr. Byrd’s proposal entitled “Effect of HELB molecular interactions on the G1-S transition” will study how protein-protein interactions facilitates formation of pre-initiation complexes and cell cycle progression, a fundamental biological process in mammalian cells that is dysregulated in cancer. Her proposal incorporates elements from the CMIC mission and the Core facilities to define and exploit the molecular interactions critical for genome stability.
Dr. Hossain’s proposal entitled “Optimizing neutrophil engagers for solid tumor immunotherapy” will pursue development of a novel biologic-based therapy to improve recognition of immunologically “cold” tumors. His COBRE-sponsored project will utilize multiple components of the CMIC Core facilities with the goal of developing novel immunotherapies for rare cancer patients with limited treatment options.
How to Acknowledge the CMIC
“Research reported in this [publication, release] was supported (in whole or in part) by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number P20GM152281. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”
For abstracts, a short note “Supported by a grant from the NIH/NIGMS – 1P20GM152281” will suffice.
Contact
Robert L. Eoff, Ph.D.
Biomedical Research Center 1
325 Jack Stephens Drive
Little Rock, AR 72210
Telephone: 501-686-8343
Email: rleoff@uams.edu