Course Director: Rosalia C.M. Simmen, Ph.D.
Office Hours: TBA, email-accessible
The course is designed to develop a foundation in human physiology by its focus on the functional activities and control mechanisms of cells, tissues and organs and the integration of organ systems to maintain homeostasis. Class lectures are supplemented with discussions of assigned papers as a forum for integrating research findings with basic concepts.
All Classes will be held in person at the Bio Med Bldg 1, Room 205/207
Monday, Wednesday and Friday
9:00 a.m. – 9:50 a.m.
Six Exams: Scheduled below from 8: 15 a.m. – 9:50 a.m.
Exam questions are short answer, essay, or multiple choice.
- Exam #1 – 1/25/2023
- Exam #2 – 2/15/2023
- Exam #3 – 3/08/2023
- Exam #5 – 4/21/2023
- Exam #6 – 5/08/2023
Textbook: Suggested textbook is Textbook of Medical Physiology, Guyton and Hall, 13th/14th Edition. Other readings will be assigned by individual instructors.
Grading: Students will be assigned a grade based on exam scores. Each teaching/learning event will have 10 points of exam question(s). Grades will be scaled, with the class average typically set at B.
Course Evaluation: The course will be evaluated by the students following UAMS procedures. Each instructor will be evaluated by the students at the end of the exam covering his/her specific course materials.
General Physiology 5103 Lecture Schedule – Spring 2023
Department of Physiology and Cell Biology
9:00 a.m. – 9:50 a.m.
|1/09/23||Endocrine Systems-General Concepts and Control Mechanisms||R. Simmen|
|1/11/23||Steroid Hormones: Mechanisms of Signal Transduction Endocrine Regulation of the Female Reproductive System||R. Simmen|
|1/13/23||Endocrine Regulation of Pregnancy and Post-Pregnancy Events||R. Simmen|
|1/16/23||Holiday (Martin Luther King, Jr. Day)|
|1/18/23||Endocrine Regulation of the Male Reproductive System||R. Simmen|
|1/20/23||Thyroid Gland and Endocrine Function||R. Simmen|
|1/23/23||Student Discussion of Assigned Papers||R. Simmen|
|1/25/23||Exam 1 (Biomed I – Room 205/207 8:15 a.m. –9:50 a.m.) Includes six learning events by R. Simmen||2 hours|
|1/27/23||The Nervous System-Cell Types and Organization||Syed|
|1/30/23||Membrane Potential, Action Potential and Synaptic Transmission||Syed|
|2/01/23||Autonomic Nervous System||Syed|
|2/03/23||Bone Biology and Metabolism||Morello|
|2/06/23||Calcium Phosphate and Bone Homeostasis||Morello|
|2/08/23||Skeletal Muscle- Structure and Regulation||Morello|
|2/11/23||Smooth Muscle- Structure and Regulation||Morello|
|2/13/23||Discussion of Assigned Papers||Morello|
|2/15/23||Exam 2 (Biomed I – Room 205/207 8:15 a.m. –9:50 a.m.) Includes 8 learning events by Syed and Morello||2 hours|
|2/17/23||Overview of the Cardiovascular System and Hemodynamics; Electrical Activity of the Heart||Jennings|
|2/20/23||Holiday (President’s Day)|
|2/22/23||Excitation-Contraction Coupling; Normal Electrocardiogram||Jennings|
|2/24/23||Heart as a Pump; Cardiac Cycle||Jennings|
|2/27/23||Microcirculation; Local and Humoral Control||Jennings|
|3/01/23||Neural Control; Blood Pressure Regulation||Jennings|
|3/03/23||Cardiac Output, Venous Return and Exercise Muscle Blood Flow||Jennings|
|3/06/23||Cardiovascular Review and/or Practice Problem Sets||Jennings|
|3/08/23||Exam 3 (Biomed I – Room 205/207 8:15 a.m. –9:50 a.m.) Includes 7 learning events by Jennings||2 hours|
|3/15/23||Principles of Gas Exchange||Jennings|
|3/17/23||Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids||Jennings|
|SPRING BREAK 3/20/23 – 3/24/23|
|3/27/23||Regulation of Respiration||Jennings|
|3/31/23||Exam 4 (Biomed I – Room 205/207 8:15 a.m. –9:50 a.m.) Includes 6 learning events by Jennings||2 hours|
|4/03/23||The Urinary System and Body Fluid Compartments||Jennings|
|4/05/23||Renal Blood Flow and Glomerular Filtration||Jennings|
|4/07/23||Solute Reabsorption and Secretion||Jennings|
|4/10/23||Urinary Concentrating and Diluting Mechanisms; Regulation of Fluid Balance||Jennings|
|4/12/23||Discussion of Assigned Papers||Jennings|
|4/14/23||Control of Acid-Base Balance by Body Buffers and the Respiratory System||Wight|
|4/17/23||Control of Acid-Base Balance by the Renal System||Wight|
|4/19/23||Analysis of Acid-Base Disturbances (computer laboratory)||Wight|
|4/21/23||Exam 5 (Biomed I – Room 205/207 8:15 a.m. –9:50 a.m.) Includes 8 learning events by Jennings and Wight||2 hours|
|4/24/23||Integrative Physiology of the GI Tract||F. Simmen|
|4/26/23||Neuro-gastroenterology and Gut Motility||F. Simmen|
|4/28/23||GI Organoids||F. Simmen|
|5/01/23||Hepatobiliary System and Exocrine Pancreas||F. Simmen|
|5/03/23||Student Discussion of Assigned Papers||F. Simmen|
|5/05/23||Student Discussion of Assigned Papers||F. Simmen|
|5/08/23||Exam 6 (Biomed I – Room 205/207 8:15 a.m. – 9:50 a.m.) Includes 6 learning events by F. Simmen||2 hours|