The goals of this course are to develop a better understanding of the molecular mechanisms underlying basic processes in cell biology. This will be achieved by discussing in depth experimental studies that lead to proposed mechanistic models. In addition, these studies will introduce you to potential experimental approaches to attack scientific questions. We encourage you to critically evaluate the experiments and to incorporate this information with that from your previous or ongoing courses and research activities.
Prior course in cell biology or permission of instructor. Biochemistry / Gene Expression is recommended. The course will be taught with the assumption that you have had courses in these areas.
Karen Abbott (Winthrop P. Rockefeller Cancer Institute, Rm. 11-111, firstname.lastname@example.org)
Paul Gottschall (Biomed 2 B341C-2, PEGottschall@uams.edu)
Thomas Kelly (Biomed 2, KellyThomasJ@uams.edu)
Vladimir Lupashin (Biomed 2 261-2, Office 501-603-1170 email@example.com)
Melda Onal (Biomed 2, Office: (501)-320-7682 Monal@uams.edu)
Brian Storrie (Biomed 2 262-2, StorrieBrian@uams.edu)
The course will be 4 credit hours; Class meetings: Tues/Fri from 9:30-11:30 in Physiology Conference Room 242-2, Biomed II (the room is reserved till 12:30 PM). The course will be a combination of lectures, weekly written work or problem sets and class discussions.
There is no required text. Molecular Cell Biology by Lodish et al is one of several textbooks that can be used for background information. Virtually all of the assigned readings will be on specific papers relevant to the topic being discussed.
For some of the sections, there will be problem sets. For other sections, there will be written assignments.
- In-class paper discussions (20%)
- Problem sets / written class assignments (20%)
- Exams (30% – 1st, 30% – 2nd)