• Skip to main content
  • Skip to main content
Choose which site to search.
University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
Department of Pharmacology and Toxicology: T-SPaT
  • UAMS Health
  • Jobs
  • Giving
  • T-SPaT Faculty
  • T-SPaT Trainees
  • T-SPaT Trainee Publications
  • Program Information
  • T-SPaT Annual Symposium
  • Program Outcomes
  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Pharmacology and Toxicology
  4. Students
  5. Graduate Program in Interdisciplinary Sciences (GPIBS)
  6. T-SPaT
  7. Program Outcomes

Program Outcomes

Recent Graduates

Jacob Edmondson, Ph.D.

Graduation Date:  May 6, 2025 (supported by SPaT Institution Match)

Dissertation Title: •Enhancing the cancer immunotherapy response through mechanisms of epigenetic control and endoplasmic reticulum stress

Current Position: •3rd Year Medical Student, University of Arkansas for Medical Sciences

Recent Publications:  Click for a full list of Dr. Edmondson’s publications

Lucy Fry, Ph.D.

Graduation Date:  April 10, 2025 (supported by NIGMS)

Dissertation Title: •Host factors in cutaneous leishmaniasis: Mechanisms of inflammatory response, lymphatic remodeling, and protective immunity

Current Position: Postdoctoral Fellow, Anschutz School of Medicine, University of Colorado

Recent Publications:  Click for a full list of Dr. Fry’s publications

Luke Childress, Ph.D.

Graduation Date:  April 22, 2025 (supported by NIGMS)

Dissertation Title: •Contributions of cellular senescence to inferior articular cartilage healing by endogenous mesenchymal progenitor cells

Current Position: Postdoctoral Fellow, Trinity College (Dublin Ireland)

Recent Publications:  Click for a full list of Dr. Childress’ publications

Ravi Sun, Ph.D.

Graduation Date:  May 1, 2024 (supported by SPaT Institution Match)

Dissertation Title: Genetic and Epigenetic Dysregulation Drive Growth of Cystic Lymphatic Malformation by Activating Pro-Proliferative Signaling Cascades

Current Position: 4th Year Medical Student, University of Arkansas for Medical Sciences

Recent Publications:  Click for a full list of Dr. Sun’s publications

Lance Benson, Ph.D. 

Graduation Date:  June 22, 2023 (supported by NIGMS)

Dissertation Title: CD8+ T Cells Mediate the Immuno-Pathogenesis of Salt-Sensitive Hypertension

Current Position: Postdoctoral Fellow, University of Alabama at Birmingham

Recent Publications:  Click for a full list of Dr. Benson’s publications

Kalee Holloway, Ph.D. 

Graduation Date:  June 22, 2023 (supported by NIGMS)

Dissertation Title: Ethanol Effects on the Brain in Animal Models of Fetal Alcohol Spectrum Disorders and Alcohol Use Disorder

Current Position: Medical Science Liaison, Life Molecular Imaging

Recent Publications:  Click for a full list of Dr. Holloway’s publications

Joel Vazquez, Ph.D. 

Graduation Date:  May 20, 2022 (supported by NIGMS)

Dissertation Title: Biomarkers of drug-induced liver injury:  discovery, evaluation and mechanistic insights

Current Position: Research Scientist-Toxicologist, University of Houston

Recent Publications:  Click for a full list of Dr. Vazquez’s publications

Francesca Lobianco-Farrar, M.D., Ph.D. 

Graduation Date:  May 2, 2022 (supported by NIGMS)

Dissertation Title: Targeting redox metabolism for liver cancer treatment

Current Position: Resident, Internventional Radiology, University of Illinois-Chicago

Recent Publications:  Click for a full list of Dr. Lobianco’s publications

Mary “Allie” Davis Schlieff, Ph.D. 

Graduation Date:  July 12, 2021 (supported by NIGMS)

Dissertation Title: Diphenylamine NSAIDs are bioactivated into hepatotoxic quinone-species metabolites

Current Position: Senior Chemist, Nestle Purina North America

Recent Publications:  Click for a full list of Dr. Scheliff’s publications

Caitlin Caperton, M.D., Ph.D.

Graduation Date:  May 17, 2021 (supported by SPaT Institution Match)

Dissertation Title: The dichotomous role of immune cells in thyroid cancer pathogenesis

Current Position: Resident, Psychiatry, University of Arkansas for Medical Sciences

Recent Publications:  Click for a full list of Dr. Caperton’s publications

Julia Tobacyk, Ph.D. 

Graduation Date:  May 17, 2021 (supported by NIGMS)

Dissertation Title: Developing a novel assay for measuring OMA1 activity and investigating the role of OMA1 in renal cold storage

Current Position:  Assistant Professor, South College (Knoxville, TN)

Recent Publications:  Click for a full list of Dr. Tobacyk’s publications

Brian Koss, Ph.D.

Graduation Date:  November 18, 2020 (supported by SPaT Institution Match)

Dissertation Title: Epigenetic control of Cdkn2a.Arf protects tumor-infiltrating lymphocytes from exhaustion

Current Position:  Assistant Professor, Department of Biochemistry and Molecular Biology, UAMS

Recent Publications:  Click for a full list of Dr. Koss’ publications

Brittney Garner, Ph.D.

Graduation Date:  November 13, 2020 (supported by NIGMS)

Dissertation Title: Unrecognized participation of the lymphatic system in medication side effects and development of salt-sensitive hypertension

Current Position:  Regulatory Specialist/Cook Medical

Recent Publications:  Click for a full list of Dr. Garner’s publications.

Stephen Shrum, Ph.D.

Graduation Date:  August 11, 2020 (supported by NIGMS)

Dissertation Title: The mitochondrial BK channel as a novel therapeutic target during renal cold storage and transplantation: Its role as a mitochondrial-protective factor

Current Position:  Vice President of Operations, Tocol Pharmaceuticals, LLC

Recent Publications:  Click for a full list of Dr. Shrums’s publications.

Laura Ewing, Ph.D.

Graduation Date:  July 20, 2020 (supported by NIGMS)

Dissertation Title: Determinants of radiation-induced gastrointestinal toxicity

Current Position: Toxicology and Regulatory Scientist, FDA

Recent Publications:  Click for a full list of Dr. Ewing’s publications.

Ryan MacLeod, M.D., Ph.D.

Graduation Date:  August 15, 2019 (supported by SPaT Institution Match)

Dissertation Title: Novel use of CRISPR technology to investigate bone biology

Current Position: Clinical Fellow, Yale School of Medicine

Recent Publications:  Click for a full list of Dr. MacLeod’s publications.

Charles Hay, Ph.D.

Graduation Date:  August 14, 2019 (supported by NIGMS)

Dissertation Title: The development and characterization of anti-methamphetamine antibody-based gene therapies to treat methamphetamine abuse

Current Position: Antibody Specialist, Ellie, LLC/Scientific Consultant, Global Cancer Technology

Recent Publications:  Click for a full list of Dr. Hay’s publications.

Samantha McClenahan, Ph.D.

Graduation Date:  June 19, 2019 (supported by NIGMS)

Dissertation Title: Development and testing of a vaccine for 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

Current Position:  Program Manager, Digital Medical Society

Recent Publications:  Click for a full list of Dr. McClenahan’s publications.

Bill Hyatt, M.D., M.D., Ph.D.

Graduation Date:  May 28, 2019 (supported by SPaT institution match)

Dissertation Title:  Acute and persistent impulsive effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)

Current Position:  Psychiatrist, Aspire Health

Recent Publications:  Click for a full list of Dr. Hyatt’s publications.

Daniel Meeker, M.D., Ph.D.

Graduation Date:  February 15, 2018 (supported by SPaT institution match)

Dissertation Title: Development of a targeted nanotherapeutic approach to the treatment of biofilm-associated Staphylococcus aureus infection

Current Position:  Resident, Orthopaedic Surgery, University of Iowa

Recent Publications:  Click for a full list of Dr. Meeker’s publications.

Alex W. Alund, Ph.D.

Graduation Date:  June 10, 2016 (supported by NIGMS)

Dissertation Title: The role of reactive oxygen species in alcohol-induced osteopenia and the regulation of bone turnover

Current Position: Postdoctoral fellow, Pfizer (Connecticut)

Recent Publications:  Click for a full list of Dr. Alund’s publications.

Clark R. Sims, Ph.D.

Graduation Date:  November 4, 2016 (supported by NIGMS)

Dissertation Title: Preclinical studies of targeted therapy in an infant model of sepsis-induced cardiorenal syndrome

Current Position: Assistant Staff Scientist, Arkansas Children’s Nutrition Center

Recent Publications: Click for a full list of Dr. Sims’ publications.

Emily R Holthoff, M.D., Ph.D.

Graduation Date:  May 2, 2016 (supported by SPaT institution match)

Dissertation Title: Identifying Pathologic and Molecular Features that Predict Adverse Clinical Outcomes in Vulvar Squamous Cell Carcinoma

Current Position: Resident Physician, Pediatrics, University of Arkansas for Medical Sciences

Recent Publications: Click for a full list of Dr. Holthoff’s publications.

Predoctoral Fellowships Awarded to Trainees

  • Katherine Deck – NIH/NHLBI F31HL175932 “Kidney-resident memory CD8+ T cells promote hypertension and memorize salt-sensitivity” (2024-2026)
  • Ravi Sun – NIH/NHBLI 1F30HL165803-01A1 “Altered miRNA expression drives proliferation of lymphatic malformation by activating pro-growth signaling cascade” (2023-2027)
  • Katie Deck – American Heart Association Predoctoral Fellowship 24PRE1198737 “Kidney-resident memory CD8+ T cells promote hypertension and memorize salt-sensitivity” (2024-2026)
  • Lance Benson – American Heart Association Predoctoral Fellowship 24PRE1198737 “Kidney-resident memory CD8+ T cells promote hypertension and memorize salt-sensitivity”  (2023-2025)
  • Brian Koss – NRSA NIH F31 CA232464 “Epigenetic regulation of metabolic stress pathways in melanoma infiltrating lymphocytes” (2019-2022)
  • Laura Ewing – PhRMA Foundation Predoctoral Fellowship “Role of methionine-gut microbiome interaction in radiation-induced gastrointestinal toxicity” (2019-2020)
  • Samantha McClenahan – NRSA NIH F31 DA046121 “Development of an enantiomeric specific vaccine for 3,4-methylenedioxypyrovalerone (MDPV) abuse” (2018-2021)
  • Julia Tobacyk – PhRMA Foundation Predoctoral Fellowship “The therapeutic role of OMA1 in cold storage induced nephrotoxicity” (2018-2020)
  • Stephen Shrum – American Heart Association Predoctoral 16PRE30830010 “Role of mitoBK channels in rat renal cold preservation” (2016-2018)
  • Lascelles Lyn-Cook, Jr. – Southern Regional Education Board Doctoral Scholars (2016-2017)
  • Clark Sims – NRSA NIH F31 DK104533 “Targeting renal perfusion and mitochondrial oxidants in a model of infant sepsis” (2015-2016)
  • Clark Sims – American Heart Association Predoctoral 15PRE20450050 “Renal microcirculatory failure in a rat pup model of pediatric sepsis” (2014)
  • Daniel Meeker – NRSA NIH F31 (recommended for funding, 2017)

Time to degree for SPaT trainees (Ph.D. only)

4.5 years

UAMS College of Medicine LogoUAMS College of MedicineUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
  • Facebook
  • X
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy Statement
  • Legal Notices

© 2026 University of Arkansas for Medical Sciences