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  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Biochemistry and Molecular Biology
  4. News
  5. Page 8

News

Congratulations to West Central Regional Science Fair winners

Picture of science fair winners with their teachers at ASMSA
Dr. Patrycja Krakowiak, Hannah Taylor, Gisselle Ellington, Aarohi Sonputri, Carmella Lewis, and Dr. Whitney Holden

High school students from the Arkansas School for Mathematics, Sciences and the Arts who performed their capstone research projects in the Biochemistry and Molecular Biology Department at UAMS won multiple awards at the West Central Regional Science Fair on February 23, 2024. Congratulations to all of these students and their teachers!

  • Aarohi Sonputri won first place overall and first place in the Cellular and Molecular Biology category. Aarohi also won several special awards: the Regeneron Biomedical Science Award for outstanding project in translational medical science, microbiology or medical science, Regeneron Science Talent Search Recognition, and the Winthrop Rockefeller Cancer Center Award for an outstanding project in cancer research. Her project was “Small Molecule Stabilization of the CARD11 G-Quadruplex Represses Transcription: Developing a Therapeutic Target for Diffuse Large B Cell Lymphoma.” Aarohi performed her research in Dr. Samantha Kendrick‘s laboratory.
  • Carmella Lewis won second place in the Cellular and Molecular Biology category and the Society for In-vitro Biology award for outstanding 11th-grade life science project. Carmella’s project was “DNA Unwinding Temperature of a Helicase Critical for Efficacy of Cancer Therapy.” She performed her research in Dr. Alicia Byrd‘s laboratory.
  • Gisselle Ellington won second place in the Medicine and Health Sciences category and Regeneron Science Talent Search Recognition. Giselle’s project was, “Investigating the Role of WRN Helicase in Aiding Translesion Synthesis Past G-Quadruplex Structures.” She performed her research in Dr. Robert Eoff‘s laboratory.
  • Hannah Taylor won third place in the Cellular and Molecular Biology category. Her project was “Post-Translational Modification of HELB and its Effect on Unwinding DNA.” Hannah performed her research in Dr. Alicia Byrd‘s laboratory.

Filed Under: Department News

February 2024 publications

Kim Stephens, Ph.D.

Impact of psychosocial factors on the success of neuromodulation treatment for patients with persistent pain.
Goree JH, Payakachat N, Byers L, Smith GL, Shah JR, Stephens KE.
Reg Anesth Pain Med.


Laxmi Yeruva

The Role of Early Life Gut Mycobiome on Child Health.
Rodriguez KA, Gurung M, Talatala R, Rearick JR, Ruebel ML, Stephens KE, Yeruva L.
Adv Nutr.

Filed Under: Department News

January 2024 publications

Brian Koss

Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia.
Frett B, Stephens KE, Koss B, Melnyk S, Farrar J, Saha D, Roy Choudhury S.
Cancer Sci. 2024

Filed Under: Department News

Reham Sewilam receives travel award

Reham Sewilam

Congratulations to Reham Sewilam for being awarded a Graduate Student Travel Award for the American Society for Biochemistry and Molecular Biology (ASBMB) meeting in San Antonio. Reham is a Ph.D. student in Dr. Robert Eoff‘s lab.

Filed Under: Department News

December 2023 Publications

picture of Miller lab members

The role of cytochrome P450 3A4-mediated metabolism in sorafenib and lapatinib hepatotoxicity.
McGill MR, Kaufman YJ, LoBianco FV, Schleiff MA, Aykin-Burns N, Miller GP.
Livers. 2023


Miousse lab

Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation.
Garg TK, Garg S, Miousse IR, Wise SY, Carpenter AD, Fatanmi OO, van Rhee F, Singh VK, Hauer-Jensen M.
Radiat Res. 2023

Filed Under: Department News

Congratulations Dr. Manna

Photo of Dr. Manna and Dr. Byrum

Congratulations to Kanishka Manna on the successful defense of his dissertation on “Techniques in Multi-Omics Data Integration to Develop a Novel Proteogenomics Framework for Identification of Proteoforms”. Dr. Manna’s advisors were Dr. Stephanie Byrum and Dr. Michael Robeson. Dr. Manna will be a computational postdoctoral scholar at Chobanian & Avedisian School of Medicine, Boston University.

Filed Under: Department News

Undergrads at Arkansas INBRE

Kate Jackson receiving an award for her poster presentation
Kate Jackson received 1st place for her presentation of the research she performed in Robert Eoff’s lab.
Daniela Perez Laguna receiving an award for her poster presentation
Daniela Perez Laguna received 2nd place for her presentation of the research she performed in Tudor Moldoveanu’s lab.

Several undergraduate students who performed summer research in the Biochemistry Department presented their research at the Arkansas INBRE fall conference.

Poster presenters included:

  • Anthony Carreira from the University of Arkansas, mentored by Wayne Wahls, Ph.D.
  • Daniela Perez Laguna from Arkansas State University, mentored by Tudor Moldoveanu, Ph.D.
  • Jeremiah Canady from the University of Central Arkansas, mentored by Isabelle Miousse, Ph.D.
  • Kate Jackson from Hendrix College, mentored by Robert Eoff, Ph.D.

Oral presenters included:

  • Tommy Caldarera from Hendrix College, mentored by Alicia Byrd, Ph.D.

Two of these students won awards for their poster presentations!

  • Kate Jackson (Eoff lab) won first place in Biological Sciences.
  • Daniela Perez Laguna (Moldoveanu lab) won second place in Biological Sciences.
Toimmy Caldarera presenting his research
Tommy Caldarera from Hendrix College gave an oral presentation on the summer research he performed in Alicia Byrd’s lab.

Filed Under: Department News

Congratulations Dr. Kelliher

Dr. Kelliher with her mentors
Dr. Kelliher with her mentors, Dr. Justin Leung and Dr. Brian Koss.

Congratulations to Jessica Kelliher on the successful defense of her dissertation on “Molecular Mechanisms of the Phospho-Ubiquitin Axis in the Response to Double-Stranded Breaks”. Jessica’s advisors were Dr. Justin Leung and Dr. Brian Koss. Dr. Kelliher will be staying at UAMS as a postdoctoral fellow in Dr. Brian Koss’s lab.

Filed Under: Department News

November 2023 publications

Members of the Rahman lab

RNA Splicing in Cancer and Targeted Therapies.
Islam MR, Nagar P, Neetole ST, Wan L, Rahman MA.
Genes (Basel). 2023


Alicja Urbaniak, Alan Tackett, and Billie Heflin

Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues.
Urbaniak A, Bathula C, Chauhan J, Rai P, Thammathong J, Clark C, Heflin B, De Loose A, Avaritt N, Rodriguez A, Tackett AJ, Sen S, Banerjee S.
Chem Biodivers. 2023


Members of the Raney lab

Pif1 Helicase Mediates Remodeling of Protein-Nucleic Acid Complexes by Promoting Dissociation of Sub1 from G-Quadruplex DNA and Cdc13 from G-Rich Single-Stranded DNA.
Chib S, Griffin WC, Gao J, Proffitt DR, Byrd AK, Raney KD.
Biochemistry. 2023


Authors

TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Zhao S, Lu J, Pan B, Fan H, Byrum SD, Xu C, Kim A, Guo Y, Kanchi KL, Gong W, Sun T, Storey AJ, Burkholder NT, Mackintosh SG, Kuhlers PC, Edmondson RD, Strahl BD, Diao Y, Tackett AJ, Raab JR, Cai L, Song J, Wang GG.
Nature. 2023


Alicja Urbaniak

Experimental pharmacology in precision medicine.
Urbaniak A, Thummel KE, Alade AN, Rettie AE, Prasad B, De Nicolò A, Martin JH, Sheppard DN, Jarvis MF.
Pharmacol Res Perspect. 2023

Filed Under: Department News

October 2023 Publications

Miousse lab members

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma.
Morehead LC, Koss B, Fil D, Heflin B, Garg S, Wallis KF, Tackett AJ, Miousse IR.
Mol Immunol. 2023


Picture of Kendrick lab members on a patio

Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma.
McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S.
Mol Cancer Ther. 2023


Miousse lab

Characterization of methionine dependence in melanoma cells.
Garg S, Morehead LC, Bird JT, Graw S, Gies A, Storey AJ, Tackett AJ, Edmondson RD, Mackintosh SG, Byrum SD, Miousse IR.
Mol Omics. 2023


Kim Stephens, Ph.D.

Identification of Regulatory Elements in Primary Sensory Neurons Involved in Trauma-Induced Neuropathic Pain.
Stephens KE, Moore C, Vinson DA, White BE, Renfro Z, Zhou W, Ji Z, Ji H, Zhu H, Guan Y, Taverna SD.
Mol Neurobiol. 2023

Filed Under: Department News

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