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College of Medicine: Department of Pathology

Experimental Pathology

Director:  Steven Post, Ph.D.

Mission

To provide the Department of Pathology with a recognized research program that furthers our understanding of the pathogenesis, diagnosis, and treatment of disease.

Objectives

  • To integrate clinical and basic research efforts within the Department of Pathology
  • To facilitate intra- and inter- departmental collaborations

Faculty Profiles 

  • Lu Dai, M.D.: Cancer stem cells (CSCs), molecule mechanisms of CSCs in cancer progression, developing strategies to target CSCs.
  • Behjatolah Karbassi, Ph.D.: Tumor glycobiology and metastasis, and tumor immunotherapy
  • Thomas Kelly, Ph.D: Stromal cell interactions in cancer growth, invasion, and metastasis
  • Yong-Chen William Lu, Ph.D.: T cell-based immunotherapies, cancer antigens, patient-specific mutated antigens, single-cell sequencing technologies.
  • Bolni Marius Nagalo, Ph.D.: Translational virotherapy, hepatocellular carcinoma (HCC), gene therapy for hepatobiliary and pancreatic cancers, health disparities in liver cancer, cancer therapy, and cancer-focused research.
  • Mayumi Nakagawa, M.D., Ph.D.: Cell-mediated immunity to human papillomaviruses (HPV) and developing HPV therapeutic vaccines
  • Steven Post, Ph.D. : Macrophages, scavenger receptors, and the tumor microenvironment.
  • Zhiqiang Qin, M.D., Ph.D.: Primary effusion lymphoma (PEL) and Kaposi’s sarcoma (KS), Kaposi’s sarcoma-related herpesvirus (KSHV), viral oncogenesis, virus-associated malignancies.

Translational Pathology Shared Resources

The Translational Pathology Shared Resource includes the Experimental Pathology Core Lab and the UAMS Tissue Biorepository and Procurement Service (TBAPS).

The Experimental Pathology Core Laboratory provides UAMS researchers with centralized, comprehensive histological services. Jennifer James serves as the manager of this lab.

The UAMS Tissue Biorepository and Procurement Service is an institution-wide tissue procurement facility that coordinates and oversees the donation, processing, storage, and dissemination of tissue specimens and related data. Remelle Eggerson serves as manager of this facility.

Pathobiology Graduate Track

Pathobiology is an interdisciplinary field that strives to understand the mechanisms of disease at fundamental levels. The Pathobiology Track is an option for graduate students enrolled in the GPIBS program at UAMS. The Pathobiology Track offers students a flexible program of advanced study and research in experimental pathobiology, and the opportunity to be mentored by a wide range of basic science and clinical faculty who share a common interest in understanding the molecular basis of human disease. The Pathobiology Track offers flexibility in its program to permit each student to pursue the most effective course of study and research.

Research Links