Lithium enhances repair of IR-induced DSBs in hippocampal neurons.
Lithium enhanced the percentage of cells with IR-induced T2609 foci in mouse HT-22 neuronal cells via induction of DNA-PK dependent NHEJ repair.
Inhibition of the PKM2 gene (accompany 2 Gy/each radiation) will significantly decrease the tumor volume.
Inhibition of the PKM2 gene (accompany 4 Gy/each radiation) will significantly increase the survival.
Population with higher PKM expression will have lower survival.
Imagological and histological examination with shPKM2.
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