Dr. Se-Ran Jun, Assistant Professor in the Department of Biomedical Informatics, postdoctoral fellow Dr. Zulema Udaondo, and colleagues have published a paper in Microbial Genomics.
Dr. Udaondo is first author and Dr. Jun is senior author on the study, which provides novel insights into how resistance to daptomycin – an antibiotic used to treat serious bacterial infections – disseminates, revealing a new therapeutic target.
Through big data analysis, the team was the first to identify the putative implication of composite transposons (transposable DNA sequences) in the molecular mechanism of dissemination of daptomycin resistance.