Dr. Donald Johann, Associate Professor of Biomedical Informatics and Internal Medicine, authored a paper in the high-impact journal Nature Scientific Data on the analytic validity of liquid biopsies.
The use of routine blood draws to diagnose and monitor the status of cancer patients, rather than tissue biopsies, is revolutionizing the practice of clinical oncology and how drugs are designed.
Dr. Johann has been at the forefront of research such as this to understand the analytical validity (performance) and technical limitations of this technology. The study generated the most comprehensive public-facing dataset of its kind, providing valuable insights into ultra-deep circulating tumor DNA (ctDNA, or liquid biopsy) sequencing technology.