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College of Medicine: Department of Biomedical Informatics

ALS

RNA-Seq Analysis of Spinal Cord Tissues from hPFN1G118V Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease

Barham C1, Fil D1,2, Byrum SD3, Rahmatallah Y4, Glazko G4, Kiaei M5,6,7. Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that leads to the loss of motor neurons. The molecular mechanisms of motor neuron degeneration are largely unknown and there are currently no effective therapies to treat this disease. In this work, we report whole transcriptome profiling of […]