• Skip to primary navigation
  • Skip to main content
  • Skip to primary navigation
  • Skip to main content
Choose which site to search.
University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
College of Medicine: Department of Biomedical Informatics
  • UAMS Health
  • Jobs
  • Giving
  • About Us
    • Employment
    • Access, Opportunity, and Advocacy
      • About DBMI-AOA
      • Current DBMI-AOA Committee Members
      • DBMI-AOA Resources
      • DBMI-AOA Committee Events
    • Links
    • News
    • Department Intranet
  • Faculty & Staff
    • Primary Faculty
    • Secondary Faculty
    • Adjunct Faculty
    • Staff
  • Education
    • Admission Information
    • Clinical Informatics Fellowship
      • Fellowship Overview
      • Training Sites
      • Faculty
      • Current Fellows
      • Welcome to Little Rock!
    • Graduate Programs
    • Current Course Offerings
    • DBMI FAQs
    • Research & Application Seminar
    • Recorded Sessions for CME Credit
    • Student Funding Opportunities
    • Graduate Students
  • Cores and Shared Resources
    • Arkansas Clinical Data Repository (AR-CDR)
    • Bioinformatics Collaborative Resource Center
    • INBRE
      • INBRE Bioinformatics Core Support Request Form
  • Research
    • Databases
    • Research Labs
      • Biomedical Ontologies Arkansas (BOAR)
    • Publications
  • Artificial Intelligence for Health
  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Biomedical Informatics
  4. News
  5. Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass

Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass

Biotechnology for Biofuels | 2017 | DOI: https://doi.org/10.1186/s13068-016-0697-5

Suresh Poudel, Richard J. Giannone, Miguel Rodriguez Jr., Babu Raman, Madhavi Z. Martin, Nancy L. Engle, Jonathan R. Mielenz, Intawat Nookaew, Steven D. Brown, Timothy J. Tschaplinski, David Ussery, Robert L. Hettich

Abstract

Clostridium thermocellum is capable of solubilizing and converting lignocellulosic biomass into ethanol. Although much of the work-to-date has centered on characterizing this microbe’s growth on model cellulosic substrates, such as cellobiose, Avicel, or filter paper, it is vitally important to understand its metabolism on more complex, lignocellulosic substrates to identify relevant industrial bottlenecks that could undermine efficient biofuel production. To this end, we have examined a time course progression of C. thermocellum grown on switchgrass to assess the metabolic and protein changes that occur during the conversion of plant biomass to ethanol.

Read more: https://biotechnologyforbiofuels.biomedcentral.com/articles/10.1186/s13068-016-0697-5

Posted by Chris Lesher on January 10, 2017

Filed Under: Publications Tagged With: Babu Raman, David Ussery, Intawat Nookaew, Jonathan R. Mielenz, Madhavi Z. Martin, Miguel Rodriguez Jr., Nancy L. Engle, Richard J. Giannone, Robert L. Hettich, Steven D. Brown, Suresh Poudel, Timothy J. Tschaplinski

UAMS College of Medicine LogoUAMS College of MedicineUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
  • Facebook
  • X
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy Statement

© 2025 University of Arkansas for Medical Sciences