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College of Medicine: Department of Biomedical Informatics

James Graham

Diabetes-associated alterations in the cecal microbiome and metabolome are independent of diet or environment in the UC Davis type 2-diabetes mellitus rat model

AJP-Endocrinology and Metabolism, in the press, July 2018 Brian Piccolo, James Graham, Kimber Stanhope, Intawat Nookaew, Kelly Mecer, Sree Chintapalli, Umesh Wankhade, Kartik Shankar, Peter Havel, Sean Adams Abstract Many factors contribute to, or can modify, the development of diseases such as obesity and type 2 diabetes, including the naturally occurring bacteria residing in the […]

Host diabetes status is the major regulator of gut microbiome in the UCD-T2DM Rat

The FASEB  Journal 31 (1 Supplement), 138.1-138.1(2017) Brian Piccolo, James Graham, Umesh Wankhade, Intawat Nookaew, Kartik Shankar, Peter Havel, Sean Adams Abstract There is strong evidence in humans and in animal models that the gut microbiome is altered in obesity and/or the insulin resistant condition. Poor metabolic health is often linked to overnutrition and poor-quality […]