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  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Radiology
  4. Research
  5. Ongoing Research

Ongoing Research

How to Get Involved

Join us for our monthly Radiology Research Meeting, held on the second Wednesday of the month from 12:00 to 1:00 p.m. via Zoom. Please email Dr. Xiawei Ou at OuXiawei@uams.edu for details.

If you are a student and are interested in getting involved? Please email Donna Ashlock at ashlockdonnam@uams.edu.

If you are a radiology resident and need support or guidance in research, please email Dr. Naghmeh Eshghi at NEshghi@uams.edu.

If you are a radiology faculty member and need research related support, or from another department or institution and seek for research collaboration with Department of Radiology, or have any other research related questions, please email Dr. Xiawei Ou at ouxiawei@uams.edu.

Questions or Edits?

Any questions about the information below, any additions or edits? Please email Dr. Ou at OuXiawei@uams.edu.

Active Projects

Faculty (PI) Name Project TitleResearch AreaStatusOpportunityDescription
Teresita Angtuaco, MD and Kristina Jones, MDPelvic Congestion Syndrome vs. Adenomyosis: Addressing Chronic Pelvic Pain in Womenbody imaging
William C. Culp, MD (Emritus Professor)The NOVEL Trialstrokephase 2 trialfor information purpose onlyongoing phase 2 trial of acute stroke for patented DDFPe nannodroplet
Prashanth Reddy Damalcheruvu, MDNeurometabolic Signatures of Paramagnetic Rim Lesions and their Role in Cognitive Prognosis in Multiple SclerosisNeuroradiologyFunded by Radiology faculty resaerch seed grant; IRB approval pendingthis project aims to establish the feasibility of assessing PRL-specific metabolic biomarkers that predict cognitive decline, enabling earlier intervention and patient stratification in MS clinical care and trials.
Jeff Lynch, MDHepatic pseudoaneurysm stenting using coronary covered stents Intervention Radiologyready for submission
Jeff Lynch, MDAdrenal venous sampling calculations from absent right adrenal values Intervention Radiologydata collection ongoing
Jeff Lynch, MDPost transplant hepatic artery stenting Intervention Radiologydeveloping paper
Jeff Lynch, MDAugmentation of DOTATE/Lutathera uptake in neuroendocrine cancer by pre-administration splenic embolization Intervention Radiologystudy designlooking for collabroations; need access to nuclear medicine scanners for animal models
Alex McClanahan, MD (resident)Automated Image Guidance for Endovascular Brain-Computer Interface PlacementIntervention RadiologyFunded by Radiology resident research seed grantThis project aims to develop and validate automated software for segmenting cerebral venous structures from MRI/CT and coregistering them to fluoroscopic images, enabling precise overlay of target markers on the superior sagittal sinus (SSS) for endovascular brain-computer interface (BCI) placement
Xiawei Ou, phDMaternal Obesity and Offspring Neurodevelopment: the MOON studypediatric neuroradiologyNIH funded study at Arkansas Children's Hospitallooking for residents or students to be trained and work on neuroimaging data analysisThe goal is to evaluate how maternal obesity potentially impact offspring brain structural and functional development using advanced MRI
Xiawei Ou, PhDHEALthy Brain and Child Development: the HBCD studypediatric neuroradiologyNIH funded study at Arkansas Children's HospitalLooking for students who can contribut to data collection (late night MRIs)This is a national consortium study. We are collaborating with 24 other sites in the country for this longitudinal study which will follow ~6,000 mother/child dyads from pregnancy to school age,
Xiawei Ou, PhDPeanut Consumpition and Brain Developmentpediatric neuroradiologyUSDA funded study at Arkansas Children's Hospitallooking for residents or students to be trained and work on gut microbiota and neuroimaging data analysisThis study investigates relationships between peanut consumtion during pregnancy and in early childhood and brain development and neurodevelopmental outcomes in children
Kumar Shashi, MDArteriovenous Malformations as Neoplastic-like Lesions:
Molecular Underpinnings and Implications for the Interventional Radiologist
Pediatric IRManuscript written and under review by co-authorsThis review reframes arteriovenous malformations as oncogene-driven neoplastic-like lesions and argues that the embolization procedure offers a unique opportunity for draining vein liquid biopsy to guide mutation-matched targeted therapy
Kumar Shashi, MDPercutaneous Drainage of Pneumatoceles in Neonates: A Single-Center Case SeriesPediatric IRAwaiting IRB reviewWriting up the largest reported case series of image-guided percutaneous pigtail catheter drainage of neonatal pneumatoceles, demonstrating that intervention achieves rapid resolution in days compared to the weeks-to-months expected with conservative management, in a population where watchful waiting was no longer clinically viable.
Kumar Shashi, MDPediatric Venous ThrombectomiesPediatric IRIRB done, Data collection going onMight need a student to write up the manuscriptUnderstanding the characteristics, management approaches, and outcomes of these patients in our institution to help refine future clinical decision-making and identify gaps in current practice patterns.
Kumar Shashi, MDImage-Guided Percutaneous Thyroid Ablation in the Pediatric Population: A Systematic ReviewPediatric IRAwaiting PROPERO registration.
Literature search with librarian going on under Embase/CENTRAL syntax databases
Might need a student to write up the manuscriptThis is a PRISMA-compliant systematic review evaluating the efficacy and safety of image-guided percutaneous thyroid ablation (radiofrequency, microwave, laser, and ethanol ablation) in pediatric patients under 20 years of age, a topic for which no dedicated systematic review or society guideline currently exists
Kumar Shashi, MDCurved Needle Single-Stick Technique for Pediatric Tunneled Jugular CVCs: Outcomes Stratified by Catheter Type Pediatric IRIRB exemption done. Data collection going onNeed a resident or a student for data collectionA retrospective single-institution study describing a curved needle single-stick technique for pediatric tunneled jugular central venous catheter placement and reporting catheter-subtype-stratified technical outcomes, patency, and complication rates, not previously described in the literature.

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