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College of Medicine: Department of Biomedical Informatics
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  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Biomedical Informatics
  4. Morgan GJ

Morgan GJ

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

Blood. 2018 Jun 8. pii: blood-2018-03-840132. doi: 10.1182/blood-2018-03-840132 Walker BA, Mavrommatis K, Wardell CP, Ashby TC, Bauer M, Davies FE, Rosenthal A, Wang H, Qu P, Hoering A, Samur M, Towfic F, Ortiz M, Flynt E, Yu Z, Yang Z, Rozelle D, Obenauer J, Trotter M, Auclair D, Keats J, Bolli N, Fulciniti M, Szalat […]

Filed Under: Publications Tagged With: Anderson KC, Ashby TC, Auclair D, Avet-Loiseau H, Bauer M, Bolli N, Davies FE, Durie B, Einsele H, Flynt E, Fulciniti M, Goldschmidt H, Hoering A, Jackson GH, Keats J, Lonial S, Mavrommatis K, Moreau P, Morgan GJ, Munshi N, Obenauer J, Ortiz M, Qu P, Raab MS, Rosenthal A, Rozelle D, Samur M, San Miguel J, Sonneveld P, Stewart AK, Szalat R, Thakurta A, Towfic F, Trotter M, Walker BA, Wang H, Wardell CP, Yang Z, Yu Z

Kinase domain activation through gene rearrangement in multiple myeloma

Leukemia. 2018 Mar 23. doi: 10.1038/s41375-018-0108-y Morgan GJ, He J, Tytarenko R, Patel P, Stephens OW, Zhong S, Deshpande S, Bauer M, Weinhold N, Schinke C, Rasche L, Bailey M, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Zangari M, van Rhee F, Mughal T, Davies FE, Walker BA Abstract Chromosomal rearrangements that […]

Filed Under: Publications Tagged With: Ali S, Bailey M, Bauer M, Davies FE, Deshpande S, He J, Miller VA, Morgan GJ, Mughal T, Patel P, Rasche L, Ross J, Schinke C, Stephens OW, Stephens P, Thanendrarajan S, Tytarenko R, van Rhee F, Walker BA, Weinhold N, Zangari M, Zhong S

Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?

Leukemia. 2018 Jul;32(7):1561-1566. doi: 10.1038/s41375-018-0017-0. Epub 2018 Feb 2 Pawlyn C, Loehr A, Ashby C, Tytarenko R, Deshpande S, Sun J, Fedorchak K, Mughal T, Davies FE, Walker BA, Morgan GJ Abstract PARP inhibitors can induce synthetic lethality in tumors characterized by homologous recombination deficiency (HRD), which can be detected by evaluating genome-wide loss of […]

Filed Under: Publications Tagged With: Ashby C, Davies FE, Deshpande S, Fedorchak K, Loehr A, Morgan GJ, Mughal T, Pawlyn C, Sun J, Tytarenko R, Walker BA

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target

Clin Cancer Res. 2018 May 15;24(10):2395-2407. doi: 10.1158/1078-0432.CCR-17-1594. Epub 2018 Feb 1. Fok JHL, Hedayat S, Zhang L, Aronson LI, Mirabella F, Pawlyn C, Bright MD, Wardell CP, Keats JJ, De Billy E, Rye CS, Chessum NEA, Jones K, Morgan GJ, Eccles SA, Workman P, Davies FE Abstract Myeloma is a plasma cell malignancy characterized […]

Filed Under: Publications Tagged With: Aronson LI, Bright MD, Chessum NEA, Davies FE, De Billy E, Eccles SA, Fok JHL, Hedayat S, Jones K, Keats JJ, Mirabella F, Morgan GJ, Pawlyn C, Rye CS, Wardell CP, Workman P, Zhang L

Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker

Received: 27 December 2016 | Accepted: 13 January 2017 | Published: 24 February 2017 | DOI: https://doi.org/10.1038/bcj.2017.12 Chavan SS, He J, Tytarenko R, Deshpande S, Patel P, Bailey M, Stein CK, Stephens O, Weinhold N, Petty N, Stewart D, Rasche L, Bauer M, Ashby C, Peterson EA, Ali S, Ross J, Miller VA, Stephens P, […]

Filed Under: Publications Tagged With: Ali S, Ashby C, Bailey M, Barlogie B, Bauer M, Chavan SS, Davies FE, Deshpande S, He J, Miller VA, Morgan GJ, Mughal TI, Patel P, Peterson EA, Petty N, Rasche L, Rhee van F, Ross J, Schinke C, Stein CK, Stephens O, Stephens P, Stewart D, Thanendrarajan S, Tytarenko R, Walker BA, Weinhold N, Zangari M

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