The Center for Microbial Pathogenesis
The Center for Microbial Pathogenesis and Host Inflammatory Responses provides an integrated and supportive research infrastructure that significantly enhances the ability of Project Leaders to establish independent, extramurally funded research programs. We offer a scientific and administrative foundation created under this umbrella to recruit additional junior investigators whose research interests are consistent with the underlying scientific theme and whose participation further enhances overall program synergy. The long-term goal is to integrate Project Leaders with newly recruited junior investigators, as well as with established investigators who can significantly expand their existing research programs, to create the collaborative and translational synergy required for the development of successful program-project applications.
The UAMS DNA Sequencing Core Facility has provided rapid and high quality sequencing to UAMS and surrounding colleges and universities in the state of Arkansas for over 20 years. Our current instrument is a model 3500 Applied Biosystems Genetic Analyzer and customers regularly achieve read lengths of 950 to 1000 bases. In addition to basic Sanger sequencing, we also offer Next Generation Sequencing using an Illumina Miseq. Current services are Small Genome Sequencing, 16s rRNA Metagenomics, and RNA-seq. Bioinformatics support and assistance is also available.
The Microbiology & Immunology Flow Cytometry Core Facility provides the researchers of UAMS with an immensely powerful and diverse tool to measure multiple physical characteristics of individual cells in suspension. The flow cytometer can indicate relative cell size and density or complexity by measuring forward- and side-scattered laser light, respectively. In addition, the flow cytometer can measure relative fluorescence from fluorescent probes which bind to specific cell-associated molecules.
Next Generation Sequencing
The Next Generation Sequencing Core offers the following NGS services using the Illumina Miseq. Indexing (i.e. barcoding or multiplexing) is possible enabling researchers to save time and money by running multiple samples on a single run.
The University of Arkansas for Medical Sciences (UAMS) supports a wide range of shared resources and core facilities designed to advance basic, clinical and translational research. Core facilities are pay-per-use research laboratories or analytical services, which allow investigators access to technologies and services they do not have available in their own laboratories.