Postdoctoral Fellow
Ph.D.: Washington State University, Molecular Biosciences
Hometown: Phoenix, AZ
Mentor: Daniel Voth, Ph.D.
Email:RGuzman@uams.edu
I am currently investigating the host innate immune response to Coxiella burnetii using human cell models of infection. I am also characterizing Coxiellaproteins that modulate host cell functions. My doctoral research defined Coxiella infection in fruit flies and S2 cells, and I became passionate about understanding how this highly infectious bacterium infects multiple species and cell types. Now I get to study this unique host-pathogen interface from different angles using human cell systems.
Selected publications
- Guzman RM*, Howard ZP*, Liu Z, Oliveira RD, Massa AT, Omsland A, White SN, Goodman AG. Natural genetic variation in Drosophila melanogaster reveals genes associated with Coxiella burnetii infection. Genetics. 2021 Mar. (*denotes equal contribution)
- Matz KM*, Guzman RM*, Goodman AG. The role of nucleic acid sensing in controlling microbial and autoimmune disorders. Int. Rev. Cell. Mol. Biol. 2018 Sep. (*denotes equal contribution)
- Martin M, Hiroyasu A, Guzman RM, Roberts SA, Goodman AG. Analysis of Drosophila STING reveals an evolutionarily conserved antimicrobial function. Cell Rep. 2018 Jun.