Bioorg Med Chem Lett. 2018 Jun 15;28(11):2103-2108. doi: 10.1016/j.bmcl.2018.04.035. Epub 2018 Apr 17 Boezio AA, Andrews K, Boezio C, Chu-Moyer M, Copeland KW, DiMauro EF, Foti RS, Fremeau RT Jr, Gao H, Geuns-Meyer S, Graceffa RF, Gunaydin H, Huang H, La DS, Ligutti J, Moyer BD, Peterson EA, Yu V, Weiss MM Abstract Recently, the […]
Temporal Dynamics of Gut Microbiota in Triclocarban-Exposed Weaned Rats
Authors: Rebekah C. Kennedy, Russell R. Fling, Michael S. Robeson, Arnold M. Saxton, Liesel G. Schneider, John L. Darcy, David A. Bemis, Ling Zhao, Jiangang Chen ABSTRACT: Widely used as an antimicrobial in antibacterial bar soaps, triclocarban (3,4,4′-trichlorocarbanilide; TCC) is effective against Gram-positive bacteria but shows little efficacy against Gram-negative strains, potentially altering the composition […]
The diversity and specificity of the extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic growth substrate
Biotechnol Biofuels. 2018 Mar 23 | DOI: 10.1186/s13068-018-1076-1 Poudel S, Giannone RJ, Basen M, Nookaew I, Poole FL, Kelly RM, Adams MWW, Hettich RL Abstract Caldicellulosiruptor bescii is a thermophilic cellulolytic bacterium that efficiently deconstructs lignocellulosic biomass into sugars, which subsequently can be fermented into alcohols, such as ethanol, and other products. Deconstruction of complex substrates by C. bescii involves a […]
Kinase domain activation through gene rearrangement in multiple myeloma
Leukemia. 2018 Mar 23. doi: 10.1038/s41375-018-0108-y Morgan GJ, He J, Tytarenko R, Patel P, Stephens OW, Zhong S, Deshpande S, Bauer M, Weinhold N, Schinke C, Rasche L, Bailey M, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Zangari M, van Rhee F, Mughal T, Davies FE, Walker BA Abstract Chromosomal rearrangements that […]
Modeling the Personal Health Ecosystem
Stud Health Technology Informatics. 2018;249:38-49 Blobel B, Brochhausen, Ruotsalainen P. Abstract Complex ecosystems like the pHealth one combine different domains represented by a huge variety of different actors (human beings, organizations, devices, applications, components) belonging to different policy domains, coming from different disciplines, deploying different methodologies, terminologies, and ontologies, offering different levels of knowledge, skills, […]
UAMS Team First to Add Directly Sequenced RNA to Public Database
A group of UAMS researchers is the first to deposit directly sequenced RNA to the National Center for Biotechnology Information databases, made possible by their utilization of a novel, handheld genetic sequencing technology. The federal government maintains a collection of databases with the aim of advancing science and health by providing public access to biomedical […]
Genome-Based Comparison of Clostidioides difficile: Average Amino Acid Identity Analysis of Core Genomes
Microb Ecol. 2018 Feb 14. | DOI: 10.1007/s00248-018-1155-7. Cabal A, Jun SR, Jenjaroenpun P, Wanchai V, Nookaew I, Wongsurawat T, Burgess MJ, Kothari A, Wassenaar TM, Ussery DW Abstract Infections due to Clostridioides difficile (previously known as Clostridium difficile) are a major problem in hospitals, where cases can be caused by community-acquired strains as well as […]
Genome-Based Comparison of Clostridioides difficile : Average Amino Acid Identity Analysis of Core Genomes
Adriana Cabal, Se-Ran Jun, Piroon Jenjaroenpun, Visanu Wanchai, Intawat Nookaew, Thidathip Wongsurawat, Mary J. Burgess, Atul Kothari, Trudy M. Wassenaar1, David W. Ussery Received: 30 August 2017 /Accepted: 2 February 2018 # The Author(s) 2018. This article is an open access publication Abstract Infections due to Clostridioides difficile (previously known as Clostridium difficile) are a […]
Informatics Track, First in U.S., Has Key CTSA Role
Amy Jones, M.S., often studies at a back table at Cheers in the Heights restaurant in Little Rock, where she also waitresses. Over the years she’s come to know the regulars, who include UAMS physicians and researchers. They’ve watched her grow up there, she said, and they have always encouraged her scholarship. Last summer when […]
Interspecific plant interactions reflected in soil bacterial community structure and nitrogen cycling in primary succession.
Front. Microbiology, in the press, January 2018 | doi: 10.3389/fmicb.2018.00128 https://www.frontiersin.org/articles/10.3389/fmicb.2018.00128/abstract Joseph E. Knelman, Emily B. Graham, Janet S. Prevéy, Michael S. Robeson, Patrick Kelly, Eran Hood and Steve K. Schmidt Past research demonstrating the importance plant-microbe interactions as drivers of ecosystem succession has focused on how plants condition soil microbial communities, impacting subsequent plant […]