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  1. University of Arkansas for Medical Sciences
  2. College of Medicine
  3. Department of Biomedical Informatics
  4. News
  5. Page 13

News

Genome-Based Comparison of Clostridioides difficile : Average Amino Acid Identity Analysis of Core Genomes

Adriana Cabal, Se-Ran Jun, Piroon Jenjaroenpun, Visanu Wanchai, Intawat Nookaew, Thidathip Wongsurawat, Mary J. Burgess, Atul Kothari, Trudy M. Wassenaar1, David W. Ussery Received: 30 August 2017 /Accepted: 2 February 2018 # The Author(s) 2018. This article is an open access publication Abstract Infections due to Clostridioides difficile (previously known as Clostridium difficile) are a […]

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Filed Under: Department News, Publications Tagged With: AAI .MLST, Adriana Cabal, Atul Kothari, C. difficile, Community-acquired infections, Comparative genomics, David W. Ussery, Intawat Nookaew, Mary J. Burgess, Piroon Jenjaroenpun, Se-Ran Jun, Thidathip Wongsurawat, Trudy M. Wassenaar1, Visanu Wanchai

Informatics Track, First in U.S., Has Key CTSA Role

Amy Jones, M.S., often studies at a back table at Cheers in the Heights restaurant in Little Rock, where she also waitresses. Over the years she’s come to know the regulars, who include UAMS physicians and researchers. They’ve watched her grow up there, she said, and they have always encouraged her scholarship. Last summer when […]

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Filed Under: Department News Tagged With: CTSA role, informatics track, Meredith Zozus

Interspecific plant interactions reflected in soil bacterial community structure and nitrogen cycling in primary succession.

Front. Microbiology, in the press, January 2018  | doi: 10.3389/fmicb.2018.00128 https://www.frontiersin.org/articles/10.3389/fmicb.2018.00128/abstract Joseph E. Knelman, Emily B. Graham, Janet S. Prevéy, Michael S. Robeson, Patrick Kelly, Eran Hood and Steve K. Schmidt Past research demonstrating the importance plant-microbe interactions as drivers of ecosystem succession has focused on how plants condition soil microbial communities, impacting subsequent plant […]

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Filed Under: Department News, Publications Tagged With: bacterial community, glacier forefield, Michael S. Robeson, Nitrogen Cycling, plant microbiome, Plant-microbe interaction, plant-plant interactions, primary succession, Soil

Transcriptome alterations of vascular smooth muscle cells in aortic wall of myocardial infarction patients

Data Brief. 2018 Feb 6;17:1112-1135. doi: 10.1016/j.dib.2018.01.108. eCollection 2018 Apr Wongsurawat T, Woo CC, Giannakakis A, Lin XY, Cheow ESH, Lee CN, Richards M, Sze SK, Nookaew I, Kuznetsov VA, Sorokin V Abstract This article contains further data and information from our published manuscript [1]. We aim to identify significant transcriptome alterations of vascular smooth […]

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Filed Under: Publications Tagged With: Cheow ESH, Giannakakis A, Kuznetsov VA, Lee CN, Lin XY, Nookaew I, Richards M, Sorokin V, Sze SK, Wongsurawat T, Woo CC

Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?

Leukemia. 2018 Jul;32(7):1561-1566. doi: 10.1038/s41375-018-0017-0. Epub 2018 Feb 2 Pawlyn C, Loehr A, Ashby C, Tytarenko R, Deshpande S, Sun J, Fedorchak K, Mughal T, Davies FE, Walker BA, Morgan GJ Abstract PARP inhibitors can induce synthetic lethality in tumors characterized by homologous recombination deficiency (HRD), which can be detected by evaluating genome-wide loss of […]

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Filed Under: Publications Tagged With: Ashby C, Davies FE, Deshpande S, Fedorchak K, Loehr A, Morgan GJ, Mughal T, Pawlyn C, Sun J, Tytarenko R, Walker BA

Liquid biopsy and its role in an advanced clinical trial for lung cancer

Exp Biol Med (Maywood). 2018 Feb;243(3):262-271. doi: 10.1177/1535370217750087 Johann DJ Jr, Steliga M, Shin IJ, Yoon D, Arnaoutakis K, Hutchins L, Liu M, Liem J, Walker K, Pereira A, Yang M, Jeffus SK, Peterson E, Xu J Abstract Liquid biopsy methodologies, for the purpose of plasma genotyping of cell-free DNA (cfDNA) of solid tumors, are […]

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Filed Under: Publications Tagged With: Arnaoutakis K, Hutchins L, Jeffus SK, Johann DJ Jr, Liem J, Liu M, Pereira A, Peterson E, Shin IJ, Steliga M, Walker K, Xu J, Yang M, Yoon D

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target

Clin Cancer Res. 2018 May 15;24(10):2395-2407. doi: 10.1158/1078-0432.CCR-17-1594. Epub 2018 Feb 1. Fok JHL, Hedayat S, Zhang L, Aronson LI, Mirabella F, Pawlyn C, Bright MD, Wardell CP, Keats JJ, De Billy E, Rye CS, Chessum NEA, Jones K, Morgan GJ, Eccles SA, Workman P, Davies FE Abstract Myeloma is a plasma cell malignancy characterized […]

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Filed Under: Publications Tagged With: Aronson LI, Bright MD, Chessum NEA, Davies FE, De Billy E, Eccles SA, Fok JHL, Hedayat S, Jones K, Keats JJ, Mirabella F, Morgan GJ, Pawlyn C, Rye CS, Wardell CP, Workman P, Zhang L

Genomic Characterization of biliary tract cancers identifies driver genes and predisposing mutations

J Hepatol. 2018 May;68(5):959-969. doi: 10.1016/j.jhep.2018.01.009. Epub 2018 Jan 31 Wardell CP, Fujita M, Yamada T, Simbolo M, Fassan M, Karlic R, Polak P, Kim J, Hatanaka Y, Maejima K, Lawlor RT, Nakanishi Y, Mitsuhashi T, Fujimoto A, Furuta M, Ruzzenente A, Conci S, Oosawa A, Sasaki-Oku A, Nakano K, Tanaka H, Yamamoto Y, Michiaki […]

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Filed Under: Publications Tagged With: Aikata H, Ariizumi SI, Chayama K, Conci S, Fassan M, Fujimoto A, Fujita M, Furuta M, Getz G, Gotoh K, Hatanaka Y, Hayami S, Hirano S, Karlic R, Kawakami Y, Kim J, Lawlor RT, Maejima K, Michiaki K, Mitsuhashi T, Miyano S, Nakagawa H, Nakamura T, Nakanishi Y, Nakano K, Oosawa A, Polak P, Ruzzenente A, Sasaki-Oku A, Scarpa A, Simbolo M, Tanaka H, Ueno M, Wardell CP, Yamada T, Yamamoto M, Yamamoto Y, Yamaue H

Genome Characterization of Oleaginous Aspergillus oryzae BCC7051: A Potential Fungal-Based Platform for Lipid Production

Curr Microbiol. 2018 Jan;75(1):57-70. doi: 10.1007/s00284-017-1350-7. Epub 2017 Sep 1. Thammarongtham C, Nookaew I, Vorapreeda T, Srisuk T, Land ML, Jeennor S, Laoteng K Abstract The selected robust fungus, Aspergillus oryzae strain BCC7051 is of interest for biotechnological production of lipid-derived products due to its capability to accumulate high amount of intracellular lipids using various […]

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Filed Under: Department News, Publications Tagged With: Aspergillus oryzae, Genome, Intawat Nookaew, Lipid Production

Abiotic Stresses Shift Belowground Populus-Associated Bacteria Toward a Core Stress Microbiome

mSystems, 3:e00070-17.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781258/ DOI: 10.1128/mSystems.00070-17 Abiotic Stresses Shift Belowground Populus-Associated Bacteria Toward a Core Stress Microbiome Collin M. Timm, Kelsey R. Carter, Alyssa A. Carrell, Se-Ran Jun, Sara S. Jawdy, Jessica M. Vélez, Lee E. Gunter, Zamin Yang, Intawat Nookaew, Nancy L. Engle, Tse-Yuan S. Lu, Christopher W. Schadt, Timothy J. Tschaplinski, Mitchel J. Doktycz, […]

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Filed Under: Department News, Publications Tagged With: abiotic stresses, Intawat Nookaew, microbiome

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